Bioactive glasses (BGs) have been a focus of research for over five decades for several
biomedical applications. Although their use in bone substitution and bone tissue …

Bioactive glasses (BGs) arewell known for their successful applications in tissue
engineering and regenerative medicine. Recent experimental studies have shown their …

For the treatment of tumor-related bone defects resulting from surgical resection,
simultaneous eradication of residual tumor cells and repair of bone defects represent a …

The treatment of bone cancer involves tumor resection followed by bone reconstruction of
the defect caused by the tumor using biomaterials. Additionally, post-surgery protocols cover …

Giant cell tumors of bone (GCTB) are associated with massive bone destructions and high
recurrence rates. In a previous study, we observed cytotoxic effects of three different …

Synovial inflammation in osteoarthritis (OA) is characterized by the release of cartilage-
degrading enzymes and inflammatory cytokines. 45S5-bioactive glass (45S5-BG) can …

Bone tissues are dynamically reconstructed during the entire life cycle phase, which is an
exquisitely regulated process controlled by intracellular and intercellular signals transmitted …

Despite advances in treatment modalities, bone tumour therapies still face significant
challenges. Severe side effects of conventional approaches, such as chemo-and radiation …

Despite their long history of application in orthopedics, the osteogenic and angiogenic
properties as well as the cytocompatibility and protein adsorption of the 45S5-(in wt%: 45.0 …

Many kinds of human tumors, including breast carcinomas, frequently metastasize to the
bone, making it prone to pathologic fractures. Surgical management of bone metastases …