Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier

DB Vieira, LF Gamarra - International journal of nanomedicine, 2016 - Taylor & Francis
This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …

Lipid nanoparticles functionalized with antibodies for anticancer drug therapy

AC Marques, PC Costa, S Velho, MH Amaral - Pharmaceutics, 2023 - mdpi.com
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In
the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs) …

[HTML][HTML] Polymeric nanoparticles in brain cancer therapy: A review of current approaches

CA Caraway, H Gaitsch, EE Wicks, A Kalluri, N Kunadi… - Polymers, 2022 - mdpi.com
Translation of novel therapies for brain cancer into clinical practice is of the utmost
importance as primary brain tumors are responsible for more than 200,000 deaths …

Nanoparticle strategies to improve the delivery of anticancer drugs across the blood–brain barrier to treat brain tumors

WJF Vanbilloen, JS Rechberger, JB Anderson… - Pharmaceutics, 2023 - mdpi.com
Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms
that occur within the brain and spinal cord. Although significant advances in our …

Active targeting liposome-PLGA composite for cisplatin delivery against cervical cancer

P Dana, S Bunthot, K Suktham, S Surassmo… - Colloids and Surfaces B …, 2020 - Elsevier
Cisplatin (Cis) is a widely used chemotherapeutic drug for cancer treatment. However,
toxicities and drug resistance limit the use of cisplatin. This study was aimed to improve …

Antibody conjugated nano-enabled drug delivery systems against brain tumors

BT Topçu, SB Pehlivan, Y Akdağ, MM Aşkun… - Journal of …, 2024 - Elsevier
The use of antibody-conjugated nanoparticles for brain tumor treatment has gained
significant attention in recent years. Nanoparticles functionalized with anti-transferrin …

Oleaginous microbial lipids' potential in the prevention and treatment of neurological disorders

M Alhattab, LS Moorthy, D Patel, CMM Franco, M Puri - Marine Drugs, 2024 - mdpi.com
The products of oleaginous microbes, primarily lipids, have gained tremendous attention for
their health benefits in food-based applications as supplements. However, this emerging …

VEGF-and VEGFR2-targeted liposomes for cisplatin delivery to glioma cells

SA Shein, II Kuznetsov, TO Abakumova… - Molecular …, 2016 - ACS Publications
Targeted delivery of anticancer drugs to brain tumors, especially glioblastoma multiforme,
which is the most frequent and aggressive type, is one of the important objectives in …

A window into the brain: Tools to assess pre-clinical efficacy of biomaterials-based therapies on central nervous system disorders

J Samal, AL Rebelo, A Pandit - Advanced Drug Delivery Reviews, 2019 - Elsevier
Therapeutic conveyance into the brain is a cardinal requirement for treatment of diverse
central nervous system (CNS) disorders and associated pathophysiology. Effectual …

Pharmaceutical targeting of the brain

IA Krizbai, æ# 129; dám Nyúl-Tóth… - Current …, 2016 - benthamdirect.com
Besides being indispensable for the protection and nutrition of the central nervous system
(CNS), blood-brain barrier (BBB)-forming cerebral endothelial cells (CECs) have a major …