Machine learning in preclinical drug discovery

DB Catacutan, J Alexander, A Arnold… - Nature Chemical …, 2024‏ - nature.com
Drug-discovery and drug-development endeavors are laborious, costly and time consuming.
These programs can take upward of 12 years and cost US $2.5 billion, with a failure rate of …

Natural language processing for mental health interventions: a systematic review and research framework

M Malgaroli, TD Hull, JM Zech, T Althoff - Translational Psychiatry, 2023‏ - nature.com
Neuropsychiatric disorders pose a high societal cost, but their treatment is hindered by lack
of objective outcomes and fidelity metrics. AI technologies and specifically Natural …

Large language models could change the future of behavioral healthcare: a proposal for responsible development and evaluation

EC Stade, SW Stirman, LH Ungar, CL Boland… - NPJ Mental Health …, 2024‏ - nature.com
Large language models (LLMs) such as Open AI's GPT-4 (which power ChatGPT) and
Google's Gemini, built on artificial intelligence, hold immense potential to support, augment …

The need for a measurement-based care professional practice guideline.

JF Boswell, KA Hepner, K Lysell, NE Rothrock… - …, 2023‏ - psycnet.apa.org
Professional practice guidelines (PPGs) are intended to promote a high level of professional
practice and serve as an educational resource, providing pragmatic guidance in a clinical …

Distinct roles of state-like and trait-like patient–therapist alliance in psychotherapy

S Zilcha-Mano, H Fisher - Nature Reviews Psychology, 2022‏ - nature.com
Hundreds of studies suggest that the patient–therapist alliance is the most consistent
predictor of treatment outcome across patients, therapists, types of treatment and settings …

[HTML][HTML] Evaluating the efficacy of ChatGPT in navigating the Spanish medical residency entrance examination (MIR): promising horizons for AI in clinical medicine

F Guillen-Grima, S Guillen-Aguinaga… - Clinics and …, 2023‏ - mdpi.com
The rapid progress in artificial intelligence, machine learning, and natural language
processing has led to increasingly sophisticated large language models (LLMs) for use in …

Automated evaluation of psychotherapy skills using speech and language technologies

N Flemotomos, VR Martinez, Z Chen, K Singla… - Behavior Research …, 2022‏ - Springer
With the growing prevalence of psychological interventions, it is vital to have measures
which rate the effectiveness of psychological care to assist in training, supervision, and …

[HTML][HTML] The impact of artificial intelligence on the tasks of mental healthcare workers: A sco** review

AD Rebelo, DE Verboom, NR dos Santos… - Computers in Human …, 2023‏ - Elsevier
Abstract Background Artificial Intelligence (AI) is expected to transform the work context
deeply. Currently, multiple AI systems are being studied and applied in the mental …

Understanding client reactions in online mental health counseling

A Li, L Ma, Y Mei, H He, S Zhang, H Qiu… - arxiv preprint arxiv …, 2023‏ - arxiv.org
Communication success relies heavily on reading participants' reactions. Such feedback is
especially important for mental health counselors, who must carefully consider the client's …

Nonverbal synchrony as a marker of alliance ruptures.

K Deres-Cohen, T Dolev-Amit, G Peysachov… - …, 2021‏ - psycnet.apa.org
Findings from the past 5 decades of empirical research on the working alliance suggest its
importance in psychotherapy. Recent studies have sought to identify markers of the alliance …