Zwitterionic biomaterials
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …
groups in their repeating units. When these oppositely charged groups are equally …
[HTML][HTML] Biomaterials to enhance stem cell transplantation
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …
medicine approaches and open promising avenues to repair, replace, and regenerate …
Room-temperature self-healing supramolecular polyurethanes based on the synergistic strengthening of biomimetic hierarchical hydrogen-bonding interactions and …
Develo** a new generation of polymeric materials that integrate robust mechanical
properties with ultra-high self-healing efficiency at ambient temperature remains a …
properties with ultra-high self-healing efficiency at ambient temperature remains a …
Self-healing polyurethane with high strength and toughness based on a dynamic chemical strategy
F Dong, X Yang, L Guo, Y Wang… - Journal of Materials …, 2022 - pubs.rsc.org
The introduction of disulfide bonds in polyurethane elastomers confers self-healing and
recyclable properties to the elastomers, which not only reduce the maintenance cost but also …
recyclable properties to the elastomers, which not only reduce the maintenance cost but also …
[HTML][HTML] Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus
Diabetes mellitus refers to a group of metabolic disorders which affect how the body uses
glucose impacting approximately 9% of the population worldwide. This review covers the …
glucose impacting approximately 9% of the population worldwide. This review covers the …
[HTML][HTML] Enhancing longevity of immunoisolated pancreatic islet grafts by modifying both the intracapsular and extracapsular environment
Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease characterized by
autoimmune destruction of pancreatic β cells. Transplantation of immunoisolated pancreatic …
autoimmune destruction of pancreatic β cells. Transplantation of immunoisolated pancreatic …
A century-long journey from the discovery of insulin to the implantation of stem cell–derived islets
A Ramzy, PJ Belmonte, MJS Braam, S Ida… - Endocrine …, 2023 - academic.oup.com
For the past century, insulin injections have saved millions of lives, but glycemic instability is
still a persistent challenge for people with diabetes, leading to tremendous morbidity and …
still a persistent challenge for people with diabetes, leading to tremendous morbidity and …
Engineering superstable islets-laden chitosan microgels with carboxymethyl cellulose coating for long-term blood glucose regulation in vivo
H Li, W He, Q Feng, J Chen, X Xu, C Lv, C Zhu… - Carbohydrate …, 2024 - Elsevier
Islet transplantation to restore endogenous insulin secretion is a promising therapy for type 1
diabetes in clinic. However, host immune rejection seriously limits the survival of …
diabetes in clinic. However, host immune rejection seriously limits the survival of …
Structural engineering of polyurethanes for biomedical applications
H Wang, T Li, J Li, R Zhao, A Ding, FJ Xu - Progress in Polymer Science, 2024 - Elsevier
Polyurethane, a synthetic polymer distinguished by its urethane (carbamate,-NHCOO-)
and/or urea (-NHCONH-) linkages, has been applied in various industries since its discovery …
and/or urea (-NHCONH-) linkages, has been applied in various industries since its discovery …
Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression
Islet transplantation has been established as a viable treatment modality for type 1 diabetes.
However, the side effects of the systemic immunosuppression required for patients often …
However, the side effects of the systemic immunosuppression required for patients often …