Sensing sound: Cellular specializations and molecular force sensors
Organisms of all phyla express mechanosensitive ion channels with a wide range of
physiological functions. In recent years, several classes of mechanically gated ion channels …
physiological functions. In recent years, several classes of mechanically gated ion channels …
Physics of mechanotransduction by Piezo ion channels
M Young, AH Lewis, J Grandl - Journal of General Physiology, 2022 - rupress.org
Piezo ion channels are sensors of mechanical forces and mediate a wide range of
physiological mechanotransduction processes. More than a decade of intense research has …
physiological mechanotransduction processes. More than a decade of intense research has …
Ultrafast underwater self-healing piezo-ionic elastomer via dynamic hydrophobic-hydrolytic domains
The development of advanced materials capable of autonomous self-healing and
mechanical stimulus sensing in aquatic environments holds great promise for applications in …
mechanical stimulus sensing in aquatic environments holds great promise for applications in …
Force from filaments: the role of the cytoskeleton and extracellular matrix in the gating of mechanosensitive channels
The senses of proprioception, touch, hearing, and blood pressure on mechanosensitive ion
channels that transduce mechanical stimuli with high sensitivity and speed. This conversion …
channels that transduce mechanical stimuli with high sensitivity and speed. This conversion …
Mechanosensitive membrane proteins: Usual and unusual suspects in mediating mechanotransduction
This Viewpoint, which accompanies a Special Issue focusing on membrane
mechanosensors, discusses unifying and unique features of both established and emerging …
mechanosensors, discusses unifying and unique features of both established and emerging …
An asymmetric mechanical code ciphers curvature-dependent proprioceptor activity
A repetitive gait cycle is an archetypical component within the behavioral repertoire of many
animals including humans. It originates from mechanical feedback within proprioceptors to …
animals including humans. It originates from mechanical feedback within proprioceptors to …
NOMPC ion channel hinge forms a gating spring that initiates mechanosensation
The sensation of mechanical stimuli is initiated by elastic gating springs that pull open
mechanosensory transduction channels. Searches for gating springs have focused on force …
mechanosensory transduction channels. Searches for gating springs have focused on force …
Biomotors, viral assembly, and RNA nanobiotechnology: Current achievements and future directions
Abstract The International Society of RNA Nanotechnology and Nanomedicine (ISRNN)
serves to further the development of a wide variety of functional nucleic acids and other …
serves to further the development of a wide variety of functional nucleic acids and other …
Simulation and machine learning methods for ion-channel structure determination, mechanistic studies and drug design
Ion channels are expressed in almost all living cells, controlling the in-and-out
communications, making them ideal drug targets, especially for central nervous system …
communications, making them ideal drug targets, especially for central nervous system …
Emerging roles of mechanosensitive ion channels in acute lung injury/acute respiratory distress syndrome
Q Jia, Y Yang, X Chen, S Yao, Z Hu - Respiratory Research, 2022 - Springer
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a devastating
respiratory disorder with high rates of mortality and morbidity, but the detailed underlying …
respiratory disorder with high rates of mortality and morbidity, but the detailed underlying …