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Physics-informed neural networks (PINNs) for fluid mechanics: A review
Despite the significant progress over the last 50 years in simulating flow problems using
numerical discretization of the Navier–Stokes equations (NSE), we still cannot incorporate …
numerical discretization of the Navier–Stokes equations (NSE), we still cannot incorporate …
Trauma-induced coagulopathy
Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …
Non-invasive inference of thrombus material properties with physics-informed neural networks
We employ physics-informed neural networks (PINNs) to infer properties of biological
materials using synthetic data. In particular, we successfully apply PINNs to extract the …
materials using synthetic data. In particular, we successfully apply PINNs to extract the …
Fluid mechanics of blood clot formation
Intravascular blood clots form in an environment in which hydrodynamic forces dominate
and in which fluid-mediated transport is the primary means of moving material. The clotting …
and in which fluid-mediated transport is the primary means of moving material. The clotting …
Procoagulant activity in hemostasis and thrombosis: Virchow's triad revisited
Virchow's triad is traditionally invoked to explain pathophysiologic mechanisms leading to
thrombosis, alleging concerted roles for abnormalities in blood composition, vessel wall …
thrombosis, alleging concerted roles for abnormalities in blood composition, vessel wall …
Methods of blood flow modelling
This review is devoted to recent developments in blood flow modelling. It begins with the
discussion of blood rheology and its non-Newtonian properties. After that we will present …
discussion of blood rheology and its non-Newtonian properties. After that we will present …
The use of computational fluid dynamics in the development of ventricular assist devices
Progress in the field of prosthetic cardiovascular devices has significantly contributed to the
rapid advancements in cardiac therapy during the last four decades. The concept of …
rapid advancements in cardiac therapy during the last four decades. The concept of …
Grow with the flow: a spatial–temporal model of platelet deposition and blood coagulation under flow
The body's response to vascular injury involves two intertwined processes: platelet
aggregation and coagulation. Platelet aggregation is a predominantly physical process …
aggregation and coagulation. Platelet aggregation is a predominantly physical process …
Multi-scale modelling and simulation in systems biology
The aim of systems biology is to describe and understand biology at a global scale where
biological functions are recognised as a result of complex mechanisms that happen at …
biological functions are recognised as a result of complex mechanisms that happen at …
A general shear-dependent model for thrombus formation
Modeling the transport, activation, and adhesion of platelets is crucial in predicting thrombus
formation and growth following a thrombotic event in normal or pathological conditions. We …
formation and growth following a thrombotic event in normal or pathological conditions. We …