Secreted immunomodulatory viral proteins as novel biotherapeutics
A Lucas, G McFadden - The Journal of immunology, 2004 - journals.aai.org
Many viruses have learned to evade or subvert the host antiviral immune responses by
encoding and expressing immunomodulatory proteins that protect the virus from attack by …
encoding and expressing immunomodulatory proteins that protect the virus from attack by …
[HTML][HTML] Chemokine binding proteins: An immunomodulatory strategy going viral
V González-Motos, KA Kropp… - Cytokine & growth factor …, 2016 - Elsevier
Chemokines are chemotactic cytokines whose main function is to direct cell migration. The
chemokine network is highly complex and its deregulation is linked to several diseases …
chemokine network is highly complex and its deregulation is linked to several diseases …
Human cytomegalovirus immediate-early 2 protein IE86 blocks virus-induced chemokine expression
RT Taylor, WA Bresnahan - Journal of virology, 2006 - Am Soc Microbiol
The effect of human cytomegalovirus (HCMV) gene expression on cytokine (beta interferon)
and chemokine (RANTES, MIG, MCP-2, MIP-1α, and interleukin-8) expression was …
and chemokine (RANTES, MIG, MCP-2, MIP-1α, and interleukin-8) expression was …
Targeting chemokines: Pathogens can, why can't we?
AEI Proudfoot, P Bonvin, CA Power - Cytokine, 2015 - Elsevier
Chemoattractant cytokines, or chemokines, are the largest sub-family of cytokines. About 50
distinct chemokines have been identified in humans. Their principal role is to stimulate the …
distinct chemokines have been identified in humans. Their principal role is to stimulate the …
Immune modulation by virus-encoded secreted chemokine binding proteins
Chemokines are chemoattractant cytokines that mediate the migration of immune cells to
sites of infection which play an important role in innate and adaptive immunity. As an …
sites of infection which play an important role in innate and adaptive immunity. As an …
Regulation of chemokine function: the roles of GAG-binding and post-translational nitration
The primary function of chemokines is to direct the migration of leukocytes to the site of injury
during inflammation. The effects of chemokines are modulated by several means, including …
during inflammation. The effects of chemokines are modulated by several means, including …
How microorganisms avoid phagocyte attraction
J Bestebroer, CJC De Haas… - FEMS microbiology …, 2010 - academic.oup.com
Microorganisms have developed several mechanisms to modulate the host immune system
to increase their survival and propagation in the host. Their presence in the host is not only …
to increase their survival and propagation in the host. Their presence in the host is not only …
Glycoprotein G from pseudorabies virus binds to chemokines with high affinity and inhibits their function
A Viejo-Borbolla, A Munoz… - Journal of general …, 2010 - microbiologyresearch.org
Pseudorabies virus (PRV), also known as suid herpesvirus, is the aetiological agent of
Aujeszky's disease in swine. In other animals, except higher-order primates, PRV infection is …
Aujeszky's disease in swine. In other animals, except higher-order primates, PRV infection is …
AC‐terminal CXCL 8 peptide based on chemokine–glycosaminoglycan interactions reduces neutrophil adhesion and migration during inflammation
B Martínez‐Burgo, SL Cobb, E Pohl, D Kashanin… - …, 2019 - Wiley Online Library
Leucocyte recruitment is critical during many acute and chronic inflammatory diseases.
Chemokines are key mediators of leucocyte recruitment during the inflammatory response …
Chemokines are key mediators of leucocyte recruitment during the inflammatory response …
Inhibition of intimal hyperplasia in transgenic mice conditionally expressing the chemokine-binding protein M3
R Pyo, KK Jensen, MT Wiekowski, D Manfra… - The American journal of …, 2004 - Elsevier
Chemokines have been implicated in the pathogenesis of a wide variety of diseases. This
report describes the generation of transgenic mice that conditionally express M3, a …
report describes the generation of transgenic mice that conditionally express M3, a …