The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …

Over the last five decades, a large body of evidence has accrued for structural and metabolic
brain alterations in schizophrenia. Here we provide an overview of these findings, focusing …

The transition from adolescence to adulthood is characterized by improvements in higher-
order cognitive abilities and corresponding refinements of the structure and function of the …

Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

Adolescence is a time of continued brain maturation, particularly in limbic and cortical
regions, which undoubtedly plays a role in the physiological and emotional changes …

Adolescent development is associated with major changes in emotional and cognitive
functions, as well as a rise in stress-related psychological disorders such as anxiety and …

In this paper, we provide an overview of how the maturation of specific brain regions and
stress exposure during windows of vulnerability initiate a series of events that render …

Adolescence represents a critical period for brain and behavioural health and characterised
by the onset of mood, psychotic and anxiety disorders. In rodents, neurogenesis is very …

Adverse life events are associated with a wide range of psychopathology, including an
increased risk for substance abuse. In this review, we focus on the inter-relationship …

Social play behavior is the most vigorous and characteristic form of social interaction
displayed by develo** mammals. The laboratory rat is an ideal species to study this …