RNAi efficiency, systemic properties, and novel delivery methods for pest insect control: what we know so far

MR Joga, MJ Zotti, G Smagghe… - Frontiers in physiology, 2016 - frontiersin.org
In recent years, the research on the potential of using RNA interference (RNAi) to suppress
crop pests has made an outstanding growth. However, given the variability of RNAi …

Double-stranded RNA technology to control insect pests: current status and challenges

O Christiaens, S Whyard, AM Vélez… - Frontiers in Plant …, 2020 - frontiersin.org
Exploiting the RNA interference (RNAi) gene mechanism to silence essential genes in pest
insects, leading to toxic effects, has surfaced as a promising new control strategy in the past …

Visualization of the process of a nanocarrier-mediated gene delivery: stabilization, endocytosis and endosomal escape of genes for intracellular spreading

Z Ma, Y Zheng, Z Chao, H Chen, Y Zhang… - Journal of …, 2022 - Springer
Nanoparticles have been widely applied as gene carrier for improving RNA interference
(RNAi) efficiency in medical and agricultural fields. However, the mechanism and delivery …

Next-generation insect-resistant plants: RNAi-mediated crop protection

J Zhang, SA Khan, DG Heckel, R Bock - Trends in biotechnology, 2017 - cell.com
Plant-mediated RNA interference (RNAi) shows great potential in crop protection. It relies on
plants stably expressing double-stranded RNAs (dsRNAs) that target essential genes in pest …

Towards the elements of successful insect RNAi

JG Scott, K Michel, LC Bartholomay… - Journal of insect …, 2013 - Elsevier
RNA interference (RNAi), the sequence-specific suppression of gene expression, offers
great opportunities for insect science, especially to analyze gene function, manage pest …

Universal computing by DNA origami robots in a living animal

Y Amir, E Ben-Ishay, D Levner, S Ittah… - Nature …, 2014 - nature.com
Biological systems are collections of discrete molecular objects that move around and
collide with each other. Cells carry out elaborate processes by precisely controlling these …

RNA interference in insects: protecting beneficials and controlling pests

E Vogel, D Santos, L Mingels, TW Verdonckt… - Frontiers in …, 2019 - frontiersin.org
Insects constitute the largest and most diverse group of animals on Earth with an equally
diverse virome. The main antiviral immune system of these animals is the post …

RNAi technology: a new platform for crop pest control

B Mamta, MV Rajam - Physiology and Molecular Biology of Plants, 2017 - Springer
The insect pests are big threat in meeting the food demands for future generation. The
present pest control strategies, including the existing transgenic approaches show certain …

Reduced stability and intracellular transport of dsRNA contribute to poor RNAi response in lepidopteran insects

JN Shukla, M Kalsi, A Sethi, KE Narva, E Fishilevich… - RNA biology, 2016 - Taylor & Francis
ABSTRACT RNA interference (RNAi) has become a widely used reverse genetic tool to
study gene function in eukaryotic organisms and is being developed as a technology for …

Comparative analysis of double-stranded RNA degradation and processing in insects

IK Singh, S Singh, K Mogilicherla, JN Shukla… - Scientific reports, 2017 - nature.com
RNA interference (RNAi) based methods are being developed for pest management. A few
products for control of coleopteran pests are expected to be commercialized soon. However …