Ever since Hubel and Wiesel described orientation selectivity in the visual cortex, the
question of how precise selectivity emerges has been marked by considerable debate …

To test theories of orientation selectivity in primary visual cortex (V1), we have done
experiments to measure the dynamics of orientation tuning of single neurons in the V1 …

Brain circuits process information through specialized neuronal subclasses interacting
within a network. Revealing their interplay requires activating specific cells while monitoring …

Slow oscillatory activity (< 1 Hz) is observed in vivo in the cortex during slow-wave sleep or
under anesthesia and in vitro when the bath solution is chosen to more closely mimic …

Human visual function declines with age. Much of this decline is probably mediated by
changes in the central visual pathways. We compared the stimulus selectivity of cells in …

This intracellular study investigates synaptic mechanisms of orientation and direction
selectivity in cat area 17. Visually evoked inhibition was analyzed in 88 cells by detecting …

A simple model is shown to account for a large range of V1 classical, and nonclassical,
receptive field properties including orientation tuning, spatial and temporal frequency tuning …

Neurons in primary visual cortex (V1) respond differently to a simple visual element
presented in isolation from when it is embedded withina complex image. This difference, a …

Neurons in primary visual cortex (V1) are thought to receive inhibition from other V1 neurons
selective for a variety of orientations. Evidence for this inhibition is commonly found in cross …

The responses of neurons in the primary visual cortex (V1) are suppressed by mask stimuli
that do not elicit responses if presented alone. This suppression is widely believed to be …