Nanoparticles for cancer therapy: current progress and challenges

S Gavas, S Quazi, TM Karpiński - Nanoscale research letters, 2021 - Springer
Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Nanomaterials for cancer therapy: current progress and perspectives

Z Cheng, M Li, R Dey, Y Chen - Journal of hematology & oncology, 2021 - Springer
Cancer is a disease with complex pathological process. Current chemotherapy faces
problems such as lack of specificity, cytotoxicity, induction of multi-drug resistance and stem …

Overcoming the blood–brain barrier. challenges and tricks for CNS drug delivery

LA Bors, F Erdő - Scientia Pharmaceutica, 2019 - mdpi.com
Treatment of certain central nervous system disorders, including different types of cerebral
malignancies, is limited by traditional oral or systemic administrations of therapeutic drugs …

Advances in the chemistry of dendrimers

M Sowinska, Z Urbanczyk-Lipkowska - New Journal of Chemistry, 2014 - pubs.rsc.org
Dendrimers, which are highly branched, multivalent and monodisperse polymers, have
received continuous interest in recent years because of the global demand for new …

Current progress in cancer treatment using nanomaterials

R Zhu, F Zhang, Y Peng, T **e, Y Wang, Y Lan - Frontiers in Oncology, 2022 - frontiersin.org
The pathological processes of cancer are complex. Current methods used for chemotherapy
have various limitations, such as cytotoxicity, multi-drug resistance, stem-like cells growth …

Application of stimuli responsive nanocomposites in drug delivery and theranostics to counter cancer proliferation and drug resistance

N Khanna, T Chatterji, S Singh, S Pandey - Journal of Drug Delivery …, 2023 - Elsevier
Ingenious nanomedical researches have ameliorated outcomes in cancer theranostics.
Though limitations like non specific distribution generating low signal to noise ratio in …

Nanoparticle-based approaches for treatment of hematological malignancies: a comprehensive review

U Hani, BHJ Gowda, N Haider, K Ramesh, K Paul… - AAPS …, 2023 - Springer
Blood cancer, also known as hematological malignancy, is one of the devastating types of
cancer that has significantly paved its mortality mark globally. It persists as an extremely …

Advanced nanosystems for cancer therapeutics: a review

F Mohajer, B Mirhosseini-Eshkevari… - ACS Applied Nano …, 2023 - ACS Publications
Since cancer has a very complex pathophysiology, existing cancer treatment strategies
encounter several challenges such as the lack of specificity/selectivity, induction of multidrug …

Glycosylated one-step PAMAM dendrimers loaded with methotrexate for target therapy in breast cancer cells MDA-MB-231

SA Torres-Perez, M del Pilar Ramos-Godínez… - Journal of Drug Delivery …, 2020 - Elsevier
Polyamidoamine dendrimers (PAMAM) have been extensively investigated for drug delivery
in target therapy against breast cancer and other diseases, but the development of a low …

Oligo (ethylene glycol)-based thermosensitive dendrimers and their tumor accumulation and penetration

W Wu, W Driessen, X Jiang - Journal of the American Chemical …, 2014 - ACS Publications
Dendrimers have several featured advantages over other nanomaterials as drug carriers,
such as well-defined structure, specific low-nanometer size, and abundant peripheral …