Consensus paper: cerebellum and social cognition
The traditional view on the cerebellum is that it controls motor behavior. Although recent
work has revealed that the cerebellum supports also nonmotor functions such as cognition …
work has revealed that the cerebellum supports also nonmotor functions such as cognition …
Can we safely target the WNT pathway?
M Kahn - Nature reviews Drug discovery, 2014 - nature.com
WNT–β-catenin signalling is involved in a multitude of developmental processes and the
maintenance of adult tissue homeostasis by regulating cell proliferation, differentiation …
maintenance of adult tissue homeostasis by regulating cell proliferation, differentiation …
Modeling idiopathic autism in forebrain organoids reveals an imbalance of excitatory cortical neuron subtypes during early neurogenesis
Idiopathic autism spectrum disorder (ASD) is highly heterogeneous, and it remains unclear
how convergent biological processes in affected individuals may give rise to symptoms …
how convergent biological processes in affected individuals may give rise to symptoms …
Early brain development in infants at high risk for autism spectrum disorder
Brain enlargement has been observed in children with autism spectrum disorder (ASD), but
the timing of this phenomenon, and the relationship between ASD and the appearance of …
the timing of this phenomenon, and the relationship between ASD and the appearance of …
Cortical and subcortical brain morphometry differences between patients with autism spectrum disorder and healthy individuals across the lifespan: results from the …
Objective: Neuroimaging studies show structural differences in both cortical and subcortical
brain regions in children and adults with autism spectrum disorder (ASD) compared with …
brain regions in children and adults with autism spectrum disorder (ASD) compared with …
Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases
Gene-disruptive mutations contribute to the biology of neurodevelopmental disorders
(NDDs), but most of the related pathogenic genes are not known. We sequenced 208 …
(NDDs), but most of the related pathogenic genes are not known. We sequenced 208 …
The cerebellum, sensitive periods, and autism
Cerebellar research has focused principally on adult motor function. However, the
cerebellum also maintains abundant connections with nonmotor brain regions throughout …
cerebellum also maintains abundant connections with nonmotor brain regions throughout …
The serotonin system in autism spectrum disorder: From biomarker to animal models
Elevated whole blood serotonin, or hyperserotonemia, was the first biomarker identified in
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …
FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in autism spectrum disorders
Autism spectrum disorder (ASD) is a disorder of brain development. Most cases lack a clear
etiology or genetic basis, and the difficulty of re-enacting human brain development has …
etiology or genetic basis, and the difficulty of re-enacting human brain development has …
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals
Autism spectrum disorders (ASD) are common, complex and heterogeneous
neurodevelopmental disorders. Cellular and molecular mechanisms responsible for ASD …
neurodevelopmental disorders. Cellular and molecular mechanisms responsible for ASD …