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Cardiomyopathy in children: classification and diagnosis: a scientific statement from the American Heart Association
In this scientific statement from the American Heart Association, experts in the field of
cardiomyopathy (heart muscle disease) in children address 2 issues: the most current …
cardiomyopathy (heart muscle disease) in children address 2 issues: the most current …
Left ventricular non-compaction cardiomyopathy
Left ventricular non-compaction, the most recently classified form of cardiomyopathy, is
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …
characterised by abnormal trabeculations in the left ventricle, most frequently at the apex. It …
Left ventricular noncompaction: a distinct genetic cardiomyopathy?
Left ventricular noncompaction (LVNC) describes a ventricular wall anatomy characterized
by prominent left ventricular (LV) trabeculae, a thin compacted layer, and deep …
by prominent left ventricular (LV) trabeculae, a thin compacted layer, and deep …
European heart rhythm association (EHRA)/heart rhythm society (HRS)/Asia pacific heart rhythm society (APHRS)/latin American heart rhythm society (LAHRS) expert …
Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …
Genetics of sudden cardiac death
Sudden cardiac death occurs in a broad spectrum of cardiac pathologies and is an important
cause of mortality in the general population. Genetic studies conducted during the past 20 …
cause of mortality in the general population. Genetic studies conducted during the past 20 …
Left ventricular noncompaction cardiomyopathy: cardiac, neuromuscular, and genetic factors
J Finsterer, C Stoellberger, JA Towbin - Nature Reviews Cardiology, 2017 - nature.com
Left ventricular hypertrabeculation (LVHT) or noncompaction is a myocardial abnormality of
unknown aetiology, frequently associated with monogenic disorders, particularly …
unknown aetiology, frequently associated with monogenic disorders, particularly …
Molecular regulation of cardiomyocyte differentiation
The heart is the first organ to form during embryonic development. Given the complex nature
of cardiac differentiation and morphogenesis, it is not surprising that some form of congenital …
of cardiac differentiation and morphogenesis, it is not surprising that some form of congenital …
Cardiomyopathies due to left ventricular noncompaction, mitochondrial and storage diseases, and inborn errors of metabolism
The normal function of the human myocardium requires the proper generation and utilization
of energy and relies on a series of complex metabolic processes to achieve this normal …
of energy and relies on a series of complex metabolic processes to achieve this normal …
Genetic loci associated with heart rate variability and their effects on cardiac disease risk
Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with
greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide …
greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide …
Computational analysis of the human sinus node action potential: model development and effects of mutations
Key points We constructed a comprehensive mathematical model of the spontaneous
electrical activity of a human sinoatrial node (SAN) pacemaker cell, starting from the recent …
electrical activity of a human sinoatrial node (SAN) pacemaker cell, starting from the recent …