NAPE-PLD in the ventral tegmental area regulates reward events, feeding and energy homeostasis

J Castel, G Li, O Onimus, E Leishman, PD Cani… - Molecular …, 2024 - nature.com
The N-acyl phosphatidylethanolamine-specific phospholipase D (NAPE-PLD) catalyzes the
production of N-acylethanolamines (NAEs), a family of endogenous bioactive lipids, which …

Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of Neurochondrin

E Montalban, A Giralt, L Taing, Y Nakamura, A Pelosi… - bioRxiv, 2023 - biorxiv.org
ABSTRACT BACKGROUND Highly palatable food triggers behavioral alterations
reminiscent of those induced by addictive drugs. These effects involve the reward system …

Dual role of striatal astrocytes in behavioral flexibility and metabolism in the context of obesity

E Montalban, DHM Chao, A Ansoult, C Pham, A Contini… - bioRxiv, 2023 - biorxiv.org
Brain circuits involved in metabolic control and reward-associated behaviors are potent
drivers of feeding behavior and are both dramatically altered in obesity, a multifactorial …