Preconception origins of asthma, allergies and lung function: the influence of previous generations on the respiratory health of our children
C Svanes, JW Holloway… - Journal of Internal …, 2023 - Wiley Online Library
Emerging research suggests that exposures occurring years before conception are
important determinants of the health of future offspring and subsequent generations …
important determinants of the health of future offspring and subsequent generations …
The effects of microbiota on reproductive health: A review
N Wang, L Chen, K Yi, B Zhang, C Li… - Critical Reviews in Food …, 2024 - Taylor & Francis
Reproductive issues are becoming an increasing global problem. There is increasing
interest in the relationship between microbiota and reproductive health. Stable microbiota …
interest in the relationship between microbiota and reproductive health. Stable microbiota …
Parental high-fat high-sugar diet intake programming inflammatory and oxidative parameters of reproductive health in male offspring
MN Sertorio, H César, EA de Souza… - Frontiers in Cell and …, 2022 - frontiersin.org
Parental nutrition can impact the health of future generations, programming the offspring for
the development of diseases. The develo** germ cells of the offspring could be damaged …
the development of diseases. The develo** germ cells of the offspring could be damaged …
Paternal high-fat diet altered SETD2 gene methylation in sperm of F0 and F1 mice
S Wei, S Luo, H Zhang, Y Li, J Zhao - Genes & Nutrition, 2023 - Springer
Paternal high-fat diet (HFD) can alter the epigenetics of sperm DNA, resulting in the
transmission of obesity-related traits to the offspring. Previous studies have mainly focused …
transmission of obesity-related traits to the offspring. Previous studies have mainly focused …
[HTML][HTML] Dapagliflozin ameliorates ovulation disorders via attenuating activated microglia-mediated hypothalamic inflammation in HFD-fed mice
X Chen, Z **ao, Q Liu, D Luo, Y Cai, M Fan - Neuroendocrinology, 2024 - karger.com
Introduction: Sodium-glucose cotransporter 2 inhibitors (SGLT2is) have shown
neuroprotective effects in obese mice. However, whether SGLT2i can ameliorate high-fat …
neuroprotective effects in obese mice. However, whether SGLT2i can ameliorate high-fat …
Behind the genetics: the role of epigenetics in infertility-related testicular dysfunction
A Crafa, R Cannarella, AE Calogero, S Gunes… - Life, 2024 - mdpi.com
In recent decades, we have witnessed a progressive decline in male fertility. This is partly
related to the increased prevalence of chronic diseases (eg, obesity and diabetes mellitus) …
related to the increased prevalence of chronic diseases (eg, obesity and diabetes mellitus) …
Pre-reproductive stress in adolescent female rats alters maternal care and DNA methylation patterns across generations
Stress during development affects maternal behavior and offspring phenotypes. Stress in
adolescence is particularly consequential on brain development and maturation, and is …
adolescence is particularly consequential on brain development and maturation, and is …
Taurine and its transporter TAUT positively affect male reproduction and early embryo development
H Wu, X Zhang, J Yang, T Feng, Y Chen… - Human …, 2022 - academic.oup.com
STUDY QUESTION Are taurine and its transporter TAUT associated with spermiogenesis
and early embryo development? SUMMARY ANSWER Morphologically abnormal …
and early embryo development? SUMMARY ANSWER Morphologically abnormal …
Dulaglutide reduces oxidative DNA damage and hypermethylation in the somatic cells of mice fed a high‐energy diet by restoring redox balance, inflammatory …
Obesity is an established risk factor for numerous malignancies, although it remains
uncertain whether the disease itself or weight‐loss drugs are responsible for a greater …
uncertain whether the disease itself or weight‐loss drugs are responsible for a greater …
[HTML][HTML] Exploring the Epigenetic Landscape of Spermatozoa: Impact of Oxidative Stress and Antioxidant Supplementation on DNA Methylation and …
E Hug, Y Renaud, R Guiton, M Ben Sassi, C Marcaillou… - Antioxidants, 2024 - mdpi.com
Reproductive success is dependent on gamete integrity, and oxidative stress alters male
nuclei, meaning that no DNA repair is possible due to chromatin compaction. The …
nuclei, meaning that no DNA repair is possible due to chromatin compaction. The …