Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer
agent when administered intravenously and in high doses (high-dose IVC). Early phase …

Cold atmospheric plasma (CAP) is an ionized gas, the product of a non-equilibrium
discharge at atmospheric conditions. Both chemical and physical factors in CAP have been …

Copper is an essential microelement for the body and a necessary coregulator for enzymatic
reactions, yet an unbalanced copper level promotes reactive oxidation and cytotoxicity …

Gas plasma technology generates reactive oxygen and nitrogen species (ROS/RNS),
inducing lethal oxidative damage in tumor cells. The transfer of gas plasma–derived …

Combination chemotherapy is widely exploited to overcome multidrug resistance (MDR) and
enhance the therapeutic effect of anti-tumor agents clinically. The traditional combination …

Gas plasmas, often referred to as cold physical plasma, are currently being investigated for
their potential to serve as anticancer agents. Along similar lines, gas plasma-oxidized liquids …

Rheumatoid arthritis (RA) is an autoimmune disease of the joints characterised by synovial
hyperplasia and chronic inflammation. Rheumatoid arthritis fibroblast‐like synoviocytes (RA …

The requirements for new technologies to serve as anticancer agents go far beyond their
toxicity potential. Novel applications also need to be safe on a molecular and patient level. In …

The imbalance in the proportion of M1/M2 macrophage polarization is a crucial contributor to
the persistent progression of osteoarthritis (OA). This study aimed to evaluate the effects of …

Simple Summary Pancreatic cancer is a devastating disease with high mortality. The cancer
is characterized by a dynamic and immunosuppressive tumor microenvironment (TME) with …