The golden age of transfer hydrogenation

D Wang, D Astruc - Chemical reviews, 2015 - ACS Publications
Hydrogenation is one of the most fundamental transformations in organic synthesis, and its
industrial applications span from fine chemicals to pharmaceuticals synthesis. 1− 3 Direct …

Asymmetric organocatalysis: an enabling technology for medicinal chemistry

B Han, XH He, YQ Liu, G He, C Peng… - Chemical Society Reviews, 2021 - pubs.rsc.org
The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …

Copper (I)-catalyzed asymmetric reactions involving radicals

QS Gu, ZL Li, XY Liu - Accounts of Chemical Research, 2019 - ACS Publications
Conspectus Asymmetric functionalization of alkyl radicals represents a robust yet
underdeveloped method for efficient construction and decoration of carbon skeletons in …

Quinone methides and indole imine methides as intermediates in enantioselective catalysis

X Li, Z Li, J Sun - Nature Synthesis, 2022 - nature.com
As a consequence of their propensity towards aromatization, quinone methides (QMs) and
indole imine methides (IIMs) are versatile intermediates in organic synthesis. Although QMs …

Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis

X Cheng, H Lu, Z Lu - Nature Communications, 2019 - nature.com
The asymmetric cross-coupling reaction is developed as a straightforward strategy toward 1,
1-diaryl alkanes, which are a key skeleton in a series of natural products and bioactive …

para‐Quinone Methides as Acceptors in 1,6‐Nucleophilic Conjugate Addition Reactions for the Synthesis of Structurally Diverse Molecules

CGS Lima, FP Pauli, DCS Costa… - European Journal of …, 2020 - Wiley Online Library
para‐Quinone methides (p‐QMs) are naturally occurring molecules that have been finding
increasing synthetic applications in the last few years. The presence of two electronically …

The emergence of quinone methides in asymmetric organocatalysis

L Caruana, M Fochi, L Bernardi - Molecules, 2015 - mdpi.com
Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive”
intermediates, or even as a “synthetic enigma” in organic chemistry. Indeed, there were just …

Emerging roles of in situ generated quinone methides in metal-free catalysis

AA Jaworski, KA Scheidt - The Journal of Organic Chemistry, 2016 - ACS Publications
ortho-Quinone methides have emerged recently as useful electrophiles in metal-free
catalysis. New strategies to access these species in situ that are compatible with …