Oxygen supplementation has been a mainstay in the management of patients with acute
cardiac disease. Although hypoxia is known to be detrimental, the adverse effects of …

Oxygen is toxic across all three domains of life. Yet, the underlying molecular mechanisms
remain largely unknown. Here, we systematically investigate the major cellular pathways …

Abstract Purpose of Review Cardiac magnetic resonance imaging (CMR) use in the context
of heart failure (HF) has increased over the last decade as it is able to provide detailed …

Objectives Cardiovascular magnetic resonance feature tracking (CMR-FT) is an emerging
technique for assessing myocardial strain with valuable diagnostic and prognostic potential …

Background: The pathophysiology of heart failure with preserved ejection fraction is not well
understood, but evidence strongly suggests involvement of microvascular dysfunction. We …

Purpose Gadolinium‐based dynamic susceptibility contrast (DSC) is commonly used to
characterize blood flow in patients with stroke and brain tumors. Unfortunately, gadolinium …

Objectives Atrial function can be assessed using advancing cardiovascular magnetic
resonance (CMR) post-processing methods: atrial feature tracking (FT) strain analysis or a …

Background Microvascular obstruction (MVO) and Late Gadolinium Enhancement (LGE)
assessed in cardiac magnetic resonance (CMR) are associated with adverse outcome in …

The widespread use of high-dose oxygen, to avoid perioperative hypoxemia along with
WHO-recommended intraoperative hyperoxia to reduce surgical site infections, is an …

Background: Coronary autoregulation is a feedback system, which maintains near-constant
myocardial blood flow over a range of mean arterial pressure (MAP). Yet in emergency or …