Nanocarrier drug delivery systems: characterization, limitations, future perspectives and implementation of artificial intelligence

SZ Alshawwa, AA Kassem, RM Farid, SK Mostafa… - Pharmaceutics, 2022 - mdpi.com
There has been an increasing demand for the development of nanocarriers targeting
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …

Nano-based eye drop: Topical and noninvasive therapy for ocular diseases

C Wang, Y Pang - Advanced drug delivery reviews, 2023 - Elsevier
Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Nanocarriers for ocular drug delivery: Current status and translational opportunity

S Gorantla, VK Rapalli, T Waghule, PP Singh… - RSC …, 2020 - pubs.rsc.org
Ocular diseases have a significant effect on vision and quality of life. Drug delivery to ocular
tissues is a challenge to formulation scientists. The major barriers to delivering drugs to the …

[HTML][HTML] Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances

S Jacob, AB Nair, J Shah, S Gupta, SHS Boddu… - Pharmaceutics, 2022 - mdpi.com
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

[HTML][HTML] Lipid nanoparticles for the posterior eye segment

L Bonilla, M Espina, P Severino, A Cano, M Ettcheto… - Pharmaceutics, 2021 - mdpi.com
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles,
Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for …

[HTML][HTML] Preparation and characterization of solid lipid nanoparticles encapsulated noscapine and evaluation of its protective effects against imiquimod-induced …

P Rahmanian-Devin, VR Askari, Z Sanei-Far… - Biomedicine & …, 2023 - Elsevier
Psoriasis is a chronic inflammatory skin disease characterized by thickening the epidermis
with erythema, scaling, and proliferation. Noscapine (NOS) has several anti-inflammatory …

Breaking barriers in eye treatment: Polymeric nano-based drug-delivery system for anterior segment diseases and glaucoma

KY Wu, S Ashkar, S Jain, M Marchand, SD Tran - Polymers, 2023 - mdpi.com
The eye has anatomical structures that function as robust static and dynamic barriers,
limiting the penetration, residence time, and bioavailability of medications administered …

Nanotechnology for medical and surgical glaucoma therapy—a review

ML Occhiutto, RC Maranhão, VP Costa, AG Konstas - Advances in therapy, 2020 - Springer
Glaucoma is the second leading cause of blindness worldwide. Even though significant
advances have been made in its management, currently available antiglaucoma therapies …

[HTML][HTML] Sulconazole-loaded solid lipid nanoparticles for enhanced antifungal activity: in vitro and in vivo approach

A Samee, F Usman, TA Wani, M Farooq, HS Shah… - Molecules, 2023 - mdpi.com
Solid lipid nanoparticles (SLNs) have the advantages of a cell-specific delivery and
sustained release of hydrophobic drugs that can be exploited against infectious diseases …

Valsartan solid lipid nanoparticles integrated hydrogel: A challenging repurposed use in the treatment of diabetic foot ulcer, in-vitro/in-vivo experimental study

NS El-Salamouni, MA Gowayed, NL Seiffein… - International Journal of …, 2021 - Elsevier
The article presents an experimental study on the possible repurposed use of valsartan
(Val), in the local treatment of uncontrolled diabetic foot ulcer. Solid lipid nanoparticles …