Electrochemical, electrochemiluminescent and photoelectrochemical bioanalysis of epigenetic modifiers: A comprehensive review
Epigenetic modifications mainly includes nucleic modifications and histone modifications,
which play crucial role in biological processes, such as gene and microRNA expression …
which play crucial role in biological processes, such as gene and microRNA expression …
Fluorescent nucleoside analogs: probes for investigating nucleic acid structure and function
Base‐modified fluorescent nucleoside analog probes have been very valuable in the study
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …
Methods for detection of cytosine and thymine modifications in DNA
Methylation of cytosine at the 5-position is a common epigenetic modification in mammalian
DNA and plays an important role in regulating gene expression. Oxidized derivatives of 5 …
DNA and plays an important role in regulating gene expression. Oxidized derivatives of 5 …
Selective chemical labeling of natural T modifications in DNA
We present a chemical method to selectively tag and enrich thymine modifications, 5-
formyluracil (5-fU) and 5-hydroxymethyluracil (5-hmU), found naturally in DNA. Inherent …
formyluracil (5-fU) and 5-hydroxymethyluracil (5-hmU), found naturally in DNA. Inherent …
Detection and Application of 5-Formylcytosine and 5-Formyluracil in DNA
Y Wang, X Zhang, G Zou, S Peng, C Liu… - Accounts of chemical …, 2019 - ACS Publications
Conspectus Nucleic acids contain a variety of different base modifications, such as
decoration at the fifth position of cytosine, which is one of the most important epigenetic …
decoration at the fifth position of cytosine, which is one of the most important epigenetic …
Naphthalimide derivatives as multifunctional molecules for detecting 5-formylpyrimidine by both PAGE analysis and dot-blot assays
Y Wang, C Liu, W Yang, G Zou, X Zhang… - Chemical …, 2018 - pubs.rsc.org
An azide and hydrazine tethered to a naphthalimide analogue was created to selectively
react with 5-formyluracil in one system and fluorogenically label 5-formylcytosine in another …
react with 5-formyluracil in one system and fluorogenically label 5-formylcytosine in another …
Enrichment and fluorogenic labelling of 5-formyluracil in DNA
C Liu, Y Wang, X Zhang, F Wu, W Yang, G Zou… - Chemical …, 2017 - pubs.rsc.org
Recently, the detection of natural thymine modified 5-formyluracil has attracted widespread
attention. Herein, we introduce a new insight into designing reagents for both the selective …
attention. Herein, we introduce a new insight into designing reagents for both the selective …
A highly efficient fluorescence-based switch-on detection method of 5-formyluracil in DNA
The identification of hydroxylmethyl-and formylpyrimidines in genomic DNA was a landmark
event in epigenetics. Numerous laboratories in related fields are investigating the biology of …
event in epigenetics. Numerous laboratories in related fields are investigating the biology of …
Microwave-assisted synthesis of base-modified fluorescent 1, 4-dihydropyridine nucleosides: photophysical characterization and insights
A synthesis of a small library of fluorescent 1, 4-dihydropyridine nucleoside analogues has
been successfully carried out under solvent-free conditions via a one-pot three-component …
been successfully carried out under solvent-free conditions via a one-pot three-component …
Chemoselective labeling and site‐specific map** of 5‐formylcytosine as a cellular nucleic acid modification
J Dietzsch, D Feineis, C Höbartner - FEBS letters, 2018 - Wiley Online Library
DNA methylation has a profound impact on the regulation of gene expression in normal cell
development, and aberrant methylation has been recognized as a key factor in the …
development, and aberrant methylation has been recognized as a key factor in the …