Objective To provide an update on SpaceOAR System, a Food and Drug Administration–
approved hydrogel indicated to create distance between the prostate and the rectum which …

Radiation therapy (RT) is a curative treatment modality for localized prostate cancer. Over
the past two decades, advances in technology and imaging have considerably changed RT …

Importance Perirectal spacers are intended to lower the risk of rectal toxic effects associated
with prostate radiotherapy. A quantitative synthesis of typical clinical results with specific …

Radiation therapy to treat cancer has evolved significantly since the discovery of x-rays. Yet,
radiation therapy still has room for improvement in reducing side effects and improving …

The risk of rectal toxicity during and after prostate cancer radiotherapy (RT) is common to all
treatment regimens. Hydrogel rectal spacers are increasingly being used to mitigate this risk …

Background Rectal spacers are used to limit dose to the anterior rectal wall in high dose
external beam radiation therapy of the prostate and have been shown to reduce radiation …

SpaceOAR hydrogel, a novel biodegradable spacer, is increasingly used in managing
prostate cancer patients undergoing radiation therapy to minimize rectal radiation dose and …

Radiation-induced damages are difficult to heal than normal wounds. This is because
radiation therapy could lead to an imbalanced inflammatory response, oxidative stress …

Purpose Although hydrogel spacer placement (HSP) minimizes rectal dose during prostate
cancer radiation therapy, its potential benefit for modulating rectal toxicity could depend on …

Purpose Rates of rectal toxicity after low-dose-rate (LDR) brachytherapy for prostate cancer
are dependent on rectal dose, which is associated with rectal distance from prostate and …