[HTML][HTML] Mechanisms of acetaminophen-induced liver injury and its implications for therapeutic interventions
M Yan, Y Huo, S Yin, H Hu - Redox biology, 2018 - Elsevier
Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver failure in
many developed countries. Mitochondrial oxidative stress is considered to be the …
many developed countries. Mitochondrial oxidative stress is considered to be the …
Acetaminophen hepatotoxicity
Acetaminophen (APAP) is one of the most popular and safe pain medications worldwide.
However, due to its wide availability, it is frequently implicated in intentional or unintentional …
However, due to its wide availability, it is frequently implicated in intentional or unintentional …
Akkermansia muciniphila ameliorates acetaminophen-induced liver injury by regulating gut microbial composition and metabolism
J **a, L Lv, B Liu, S Wang, S Zhang, Z Wu… - Microbiology …, 2022 - Am Soc Microbiol
The gut microbiota drives individual sensitivity to excess acetaminophen (APAP)-mediated
hepatotoxicity. It has been reported that the bacterium Akkermansia muciniphila protects …
hepatotoxicity. It has been reported that the bacterium Akkermansia muciniphila protects …
Iron-based materials for the adsorption and photocatalytic degradation of pharmaceutical drugs: a comprehensive review of the mechanism pathway
Adsorption and photocatalytic degradation techniques for removing various contaminants
have received broad consideration and acceptance due to their advantages over …
have received broad consideration and acceptance due to their advantages over …
Wearable plasmonic sweat biosensor for acetaminophen drug monitoring
Monitoring the acetaminophen dosage is important to prevent the occurrence of adverse
reactions such as liver failure and kidney damage. Traditional approaches to monitoring …
reactions such as liver failure and kidney damage. Traditional approaches to monitoring …
[HTML][HTML] Acetaminophen toxicity: novel insights into mechanisms and future perspectives
Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the US,
and decades of intense study of its pathogenesis resulted in the development of the antidote …
and decades of intense study of its pathogenesis resulted in the development of the antidote …
Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand
Introduction Paracetamol is a common agent taken in deliberate self‐poisoning and in
accidental overdose in adults and children. Paracetamol poisoning is the commonest cause …
accidental overdose in adults and children. Paracetamol poisoning is the commonest cause …
Pathophysiology of acute liver failure
Acute liver failure (ALF) is a rare syndrome resulting from an acute insult to the liver in
patients without known underlying chronic liver disease. It is characterized by loss of …
patients without known underlying chronic liver disease. It is characterized by loss of …
miR-223: an immune regulator in infectious disorders
S Yuan, Q Wu, Z Wang, Y Che, S Zheng… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are diminutive noncoding RNAs that can influence disease
development and progression by post-transcriptionally regulating gene expression. The anti …
development and progression by post-transcriptionally regulating gene expression. The anti …
Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology
Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the
United States and mechanisms of liver injury induced by APAP overdose have been the …
United States and mechanisms of liver injury induced by APAP overdose have been the …