Non-shivering thermogenesis signalling regulation and potential therapeutic applications of brown adipose tissue

Z Zhang, D Yang, J **ang, J Zhou… - … journal of biological …, 2021‏ - pmc.ncbi.nlm.nih.gov
In mammals, thermogenic organs exist in the body that increase heat production and
enhance energy regulation. Because brown adipose tissue (BAT) consumes energy and …

Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes

S Gheibi, AP Samsonov, S Gheibi, AB Vazquez… - Biochemical …, 2020‏ - Elsevier
Nitric oxide (NO) and hydrogen sulfide (H 2 S) are two gasotransmitters that are produced in
the human body and have a key role in many of the physiological activities of the various …

Insulin secretion: The nitric oxide controversy

S Gheibi, A Ghasemi - EXCLI journal, 2020‏ - pmc.ncbi.nlm.nih.gov
Nitric oxide (NO) is a gas that serves as a ubiquitous signaling molecule participating in
physiological activities of various organ systems. Nitric oxide is produced in the endocrine …

[HTML][HTML] Environmental exposure to perchlorate, nitrate, and thiocyanate in relation to obesity: a population-based study

F Zhu, M Huang, J Jiao, P Zhuang, L Mao… - Environment …, 2019‏ - Elsevier
Background Perchlorate, nitrate, and thiocyanate are well-known thyroid disrupters and may
contribute to changes in body weight. However, the associations between environmental …

Anti-obesity and anti-diabetic effects of L-citrulline are sex-dependent

F Bagheripour, S Jeddi, K Kashfi, A Ghasemi - Life Sciences, 2024‏ - Elsevier
Aims Anti-diabetic and anti-obesity effects of L-citrulline (Cit) have been reported in male
rats. This study determined sex differences in response to Cit in Wistar rats. Main methods …

Impact of different hormones on the regulation of nitric oxide in diabetes

Z Gluvic, M Obradovic, M Manojlovic, RV Giglio… - Molecular and Cellular …, 2024‏ - Elsevier
Polymetabolic syndrome achieved pandemic proportions and dramatically influenced public
health systems functioning worldwide. Chronic vascular complications are the major …

Long-term nitrate administration increases expression of browning genes in epididymal adipose tissue of male type 2 diabetic rats

S Jeddi, N Yousefzadeh, H Afzali, A Ghasemi - Gene, 2021‏ - Elsevier
Expression of browning genes are lower in both humans and animals with type 2 diabetes
(T2D). This study aims at determining effects of long-term nitrate administration on protein …

Long term sodium nitrate administration positively impacts metabolic and obesity indices in ovariectomized rats

N Yousefzadeh, S Jeddi, M Shokri, H Afzali… - Archives of medical …, 2022‏ - Elsevier
Background In postmenopausal women, nitric oxide (NO) deficiency is associated with
obesity and type 2 diabetes (T2D). This study aims at determining the long-term effects of …

Dietary inorganic nitrate attenuates hyperoxia-induced oxidative stress in obese type 2 diabetic male rats

R Norouzirad, H Gholami, M Ghanbari, M Hedayati… - Life sciences, 2019‏ - Elsevier
Aims Hyperoxia has beneficial metabolic effects in type 2 diabetes. However, hyperoxia
exacerbates already existing oxidative stress in type 2 diabetes. Nitrate, a nitric oxide donor …

Chronic nitrate administration increases the expression the genes involved in the browning of white adipose tissue in female rats

N Yousefzadeh, S Jeddi, H Afzali… - Cell Biochemistry …, 2022‏ - Wiley Online Library
Nitrate, a nitric oxide (NO) donor, has antiobesity effect in female rats. This study
hypothesized that the antiobesity effect of nitrate in female rats is due to the browning of …