The blood–brain barrier (BBB), a unique structure in the central nervous system (CNS),
protects the brain from bloodborne pathogens by its excellent barrier properties …

As a commonly used treatment method for cancer, chemotherapy is greatly limited by the
side effects of chemotherapy drugs and the multiple drug resistance that develops …

Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Prodrugs are developed to increase the therapeutic properties of drugs and reduce their
side effects. Polyprodrugs emerged as highly efficient prodrugs produced by the …

Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Photopolymerization technology to transform monomers into polymer network materials has
been widely applied to enable various conventional and emerging applications such as …

Cancer remains the leading cause of death worldwide despite advances in treatment
options for patients. As such, safe and effective therapeutics are required. Short peptides …

Cancer remains a leading cause of death worldwide with more than 10 million new cases
every year. Tumor-targeted nanomedicines have shown substantial improvements of the …

Lipid nanoparticle (LNP)–mRNA complexes are transforming medicine. However, the
medical applications of LNPs are limited by their low endosomal disruption rates, high …

Cancer-associated fibroblasts (CAFs) can either suppress or support T lymphocyte activity,
suggesting that CAFs may be reprogrammable to an immunosupportive state. Angiotensin …