The T cell memory response is a crucial component of adaptive immunity responsible for
limiting or preventing viral reinfection. T cell memory after infection with the SARS-CoV-2 …

Respiratory syncytial virus (RSV), an RNA virus spread by droplet infection that affects all
ages, is increasingly recognised as an important pathogen in adults, especially among older …

Individuals with primary and pharmacologic B cell deficiencies have high rates of severe
disease and mortality from coronavirus disease 2019 (COVID-19), but the immune …

Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been
elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 …

Summary Background Prolonged SARS-CoV-2 infections in people who are
immunocompromised might predict or source the emergence of highly mutated variants. The …

Reports of symptomatic rebound and/or test re-positivity among COVID-19 patients following
the standard five-day treatment course of nirmatrelvir/ritonavir have sparked debates …

Cellular and humoral immunity exhibit dynamic adaptation to the mutating SARS-CoV-2
virus. It is noteworthy that immune responses differ significantly, influenced by whether a …

Gene expression is subject to random perturbations that lead to fluctuations in the rate of
protein production. As a consequence, for any given protein, genetically identical organisms …

Background The humoral and T-cell responses to booster COVID-19 vaccine types in
multidisease immunocompromised individuals who do not generate adequate antibody …

Patients with autoimmune diseases are at higher risk for severe infection due to their
underlying disease and immunosuppressive treatments. In this real-world observational …