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MicroRNA-155: a master regulator of inflammation
MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …
New insights into the evasion of host innate immunity by Mycobacterium tuberculosis
Q Chai, L Wang, CH Liu, B Ge - Cellular & molecular immunology, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …
miR‐155: an important role in inflammation response
J Hu, S Huang, X Liu, Y Zhang… - Journal of immunology …, 2022 - Wiley Online Library
MicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to
posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in …
posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in …
Tuberculosis and the art of macrophage manipulation
Macrophages are first-line responders against microbes. The success of Mycobacterium
tuberculosis (Mtb) rests upon its ability to convert these antimicrobial cells into a permissive …
tuberculosis (Mtb) rests upon its ability to convert these antimicrobial cells into a permissive …
MicroRNAs at the host–bacteria interface: host defense or bacterial offense
C Aguilar, M Mano, A Eulalio - Trends in microbiology, 2019 - cell.com
MicroRNAs are a class of small noncoding RNAs that act as major post-transcriptional
regulators of gene expression. They are currently recognized for their important role in the …
regulators of gene expression. They are currently recognized for their important role in the …
Host directed therapies for tuberculosis: futures strategies for an ancient disease
I Palucci, G Delogu - Chemotherapy, 2018 - karger.com
The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis is
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …
Cell death at the cross roads of host-pathogen interaction in Mycobacterium tuberculosis infection
Tuberculosis (TB) continues to be the leading cause of death by any single infectious agent,
accounting for around 1.7 million annual deaths globally, despite several interventions and …
accounting for around 1.7 million annual deaths globally, despite several interventions and …
[HTML][HTML] MicroRNAs as major regulators of the autophagy pathway
Autophagy is a cellular stress response mechanism activation of which leads to degradation
of cellular components, including proteins as well as damaged organelles in lysosomes …
of cellular components, including proteins as well as damaged organelles in lysosomes …
Binding features and functions of ATG3
Autophagy is an evolutionarily conserved catabolic process that is essential for maintaining
cellular, tissue, and organismal homeostasis. Autophagy-related (ATG) genes are …
cellular, tissue, and organismal homeostasis. Autophagy-related (ATG) genes are …
[HTML][HTML] Tuberculosis-associated microRNAs: from pathogenesis to disease biomarkers
Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the most lethal infectious
diseases with estimates of approximately 1.4 million human deaths in 2018. M. tuberculosis …
diseases with estimates of approximately 1.4 million human deaths in 2018. M. tuberculosis …