MicroRNA-155: a master regulator of inflammation

G Mahesh, R Biswas - Journal of Interferon & Cytokine Research, 2019 - liebertpub.com
MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …

New insights into the evasion of host innate immunity by Mycobacterium tuberculosis

Q Chai, L Wang, CH Liu, B Ge - Cellular & molecular immunology, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …

miR‐155: an important role in inflammation response

J Hu, S Huang, X Liu, Y Zhang… - Journal of immunology …, 2022 - Wiley Online Library
MicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to
posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in …

Tuberculosis and the art of macrophage manipulation

S Upadhyay, E Mittal, JA Philips - Pathogens and disease, 2018 - academic.oup.com
Macrophages are first-line responders against microbes. The success of Mycobacterium
tuberculosis (Mtb) rests upon its ability to convert these antimicrobial cells into a permissive …

MicroRNAs at the host–bacteria interface: host defense or bacterial offense

C Aguilar, M Mano, A Eulalio - Trends in microbiology, 2019 - cell.com
MicroRNAs are a class of small noncoding RNAs that act as major post-transcriptional
regulators of gene expression. They are currently recognized for their important role in the …

Host directed therapies for tuberculosis: futures strategies for an ancient disease

I Palucci, G Delogu - Chemotherapy, 2018 - karger.com
The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis is
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …

Cell death at the cross roads of host-pathogen interaction in Mycobacterium tuberculosis infection

K Mohareer, S Asalla, S Banerjee - Tuberculosis, 2018 - Elsevier
Tuberculosis (TB) continues to be the leading cause of death by any single infectious agent,
accounting for around 1.7 million annual deaths globally, despite several interventions and …

[HTML][HTML] MicroRNAs as major regulators of the autophagy pathway

Y Akkoc, D Gozuacik - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Autophagy is a cellular stress response mechanism activation of which leads to degradation
of cellular components, including proteins as well as damaged organelles in lysosomes …

Binding features and functions of ATG3

D Fang, H **e, T Hu, H Shan, M Li - Frontiers in cell and …, 2021 - frontiersin.org
Autophagy is an evolutionarily conserved catabolic process that is essential for maintaining
cellular, tissue, and organismal homeostasis. Autophagy-related (ATG) genes are …

[HTML][HTML] Tuberculosis-associated microRNAs: from pathogenesis to disease biomarkers

A Sinigaglia, E Peta, S Riccetti, S Venkateswaran… - Cells, 2020 - mdpi.com
Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the most lethal infectious
diseases with estimates of approximately 1.4 million human deaths in 2018. M. tuberculosis …