Recent developments in the synthesis and biological activity of acridine/acridone analogues

M Gensicka-Kowalewska, G Cholewiński… - RSC …, 2017 - pubs.rsc.org
Many people in the world struggle with cancer or bacterial, parasitic, viral, Alzheimer's and
other diseases. Therefore, many scientists seek new, more effective, more selective and less …

Antiplasmodial and antimalarial activities of quinolone derivatives: An overview

YL Fan, XW Cheng, JB Wu, M Liu, FZ Zhang… - European Journal of …, 2018 - Elsevier
Malaria remains one of the most deadly infectious diseases globally. Considering the
growing spread of resistance, development of new and effective antimalarials remains an …

Synthesis of cyclohexanones by a tandem photocatalyzed annulation

AV Bay, EJ Farnam, KA Scheidt - Journal of the American …, 2022 - ACS Publications
The rapid synthesis of cyclic scaffolds is of high importance to the chemistry community.
Strategies for the convergent synthesis of substituted carbocycles and heterocycles remain …

Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses

V Napolitano, A Dabrowska, K Schorpp, A Mourao… - Cell Chemical …, 2022 - cell.com
The COVID-19 pandemic caused by SARS-CoV-2 has been socially and economically
devastating. Despite an unprecedented research effort and available vaccines, effective …

Nickel‐asparagine complex fixed on a magnetic substrate as a precursor for preparing substituted acridines

M Abbaszadehghan… - Applied …, 2023 - Wiley Online Library
In this work, an efficient, novel, retrievable, and magnetic heterogeneous nanocatalyst,
Fe3O4@ CPTMS@ Asp@ Ni was successfully fabricated using Fe3O4 nanoparticles as the …

Synthesis of novel cytotoxic tetracyclic acridone derivatives and study of their molecular docking, ADMET, QSAR, bioactivity and protein binding properties

R Veligeti, RB Madhu, J Anireddy, VR Pasupuleti… - Scientific Reports, 2020 - nature.com
Acridone based synthetic and natural products with inherent anticancer activity advancing
the research and generating a large number of structurally diversified compounds. In this …

Design, synthesis and evaluation of acridine and fused-quinoline derivatives as potential anti-tuberculosis agents

GC Muscia, GY Buldain, SE Asís - European journal of medicinal chemistry, 2014 - Elsevier
The synthesis of twelve acridine and polycyclic acridine derivatives prepared via the
Friedländer reaction is described. The one-pot reactions of 2-amino-5-chloro or 5-nitro …

Functionalized Multi‐Walled Carbon Nanotubes (f‐MWCNT) as Highly Efficient and Reusable Heterogeneous Catalysts for the Synthesis of Acridinedione Derivatives

R Ulus, Y Yıldız, S Eriş, B Aday, F Şen… - ChemistrySelect, 2016 - Wiley Online Library
Addressed herein, carboxylic acid groups were immobilized onto carbon nanotubes and
their catalytic properties were examined for the first time for the synthesis of acridinedione …

Synthesis of aminobenzoic acid derivatives via chemoselective carbene insertion into the− NH bond catalyzed by Cu (I) complex

K Ramakrishna, C Sivasankar - The Journal of Organic Chemistry, 2016 - ACS Publications
Phosphine ligand stabilized air-stable Cu (I) complexes have been successfully used to
functionalize the aromatic aminobenzoic acids in a chemoselective manner without …

Palladium-catalyzed conversion of phenols into tetrahydroacridines

J Yu, R Zhan, CJ Li, H Zeng - Green Chemistry, 2024 - pubs.rsc.org
Phenols are readily available through the degradation of lignin, a naturally abundant and
renewable resource. The acridine skeleton, commonly found in drug molecules, holds …