A review of 3D polymeric scaffolds for bone tissue engineering: principles, fabrication techniques, immunomodulatory roles, and challenges

AG Abdelaziz, H Nageh, SM Abdo, MS Abdalla… - Bioengineering, 2023 - mdpi.com
Over the last few years, biopolymers have attracted great interest in tissue engineering and
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …

Natural polymeric scaffolds in bone regeneration

M Filippi, G Born, M Chaaban… - … in bioengineering and …, 2020 - frontiersin.org
Despite considerable advances in microsurgical techniques over the past decades, bone
tissue remains a challenging arena to obtain a satisfying functional and structural restoration …

[HTML][HTML] The application of hyaluronic acid in bone regeneration

P Zhai, X Peng, B Li, Y Liu, H Sun, X Li - International journal of biological …, 2020 - Elsevier
Hyaluronic acid (HA) exists naturally as an important component of the extracellular matrix
(ECM) in the human body. In recent decades, HA has been widely used in bone …

Bone tissue engineering via growth factor delivery: from scaffolds to complex matrices

TM De Witte, LE Fratila-Apachitei… - Regenerative …, 2018 - academic.oup.com
In recent years, bone tissue engineering has emerged as a promising solution to the
limitations of current gold standard treatment options for bone related-disorders such as …

[HTML][HTML] Recent progress in hyaluronic-acid-based hydrogels for bone tissue engineering

HS Hwang, CS Lee - Gels, 2023 - mdpi.com
Hydrogel-based bone tissue engineering is a potential strategy for treating bone
abnormalities and fractures. Hyaluronic acid (HA) is a natural polymer that is widely …

Manufacturing of hydrogel biomaterials with controlled mechanical properties for tissue engineering applications

A Vedadghavami, F Minooei, MH Mohammadi… - Acta biomaterialia, 2017 - Elsevier
Hydrogels have been recognized as crucial biomaterials in the field of tissue engineering,
regenerative medicine, and drug delivery applications due to their specific characteristics …

[HTML][HTML] Advances in growth factor delivery for bone tissue engineering

ÉR Oliveira, L Nie, D Podstawczyk… - International journal of …, 2021 - mdpi.com
Shortcomings related to the treatment of bone diseases and consequent tissue regeneration
such as transplants have been addressed to some extent by tissue engineering and …

Natural‐based nanocomposites for bone tissue engineering and regenerative medicine: A review

S Pina, JM Oliveira, RL Reis - Advanced Materials, 2015 - Wiley Online Library
Tissue engineering and regenerative medicine has been providing exciting technologies for
the development of functional substitutes aimed to repair and regenerate damaged tissues …

Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules

MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …

Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies

MA Fernandez-Yague, SA Abbah, L McNamara… - Advanced drug delivery …, 2015 - Elsevier
The development of responsive biomaterials capable of demonstrating modulated function
in response to dynamic physiological and mechanical changes in vivo remains an important …