Recent advances in supramolecular analytical chemistry using optical sensing

L You, D Zha, EV Anslyn - Chemical reviews, 2015 - ACS Publications
The field of supramolecular chemistry has been flourishing since J.-M. Lehn, DJ Cram, and
CJ Pedersen were awarded the 1987 Nobel Prize in Chemistry. By Prof. Lehn's definition, 1 …

Synthetic materials at the forefront of gene delivery

I Lostalé-Seijo, J Montenegro - Nature Reviews Chemistry, 2018 - nature.com
The delivery of nucleic acids with transient activity for genetic engineering is a promising
methodology with potential applications in the treatment of diseases ranging from cancer …

Growing prospects of dynamic covalent chemistry in delivery applications

S Ulrich - Accounts of chemical research, 2019 - ACS Publications
Conspectus Delivery remains a major obstacle restricting the potential action of small
molecular drugs as well as novel biologics which cannot readily enter cells without the help …

Dynamic combinatorial/covalent chemistry: a tool to read, generate and modulate the bioactivity of compounds and compound mixtures

A Herrmann - Chemical Society Reviews, 2014 - pubs.rsc.org
Reversible covalent bond formation under thermodynamic control adds reactivity to self-
assembled supramolecular systems, and is therefore an ideal tool to assess complexity of …

Enhanced mRNA delivery into lymphocytes enabled by lipid-varied libraries of charge-altering releasable transporters

CJ McKinlay, NL Benner, OA Haabeth… - Proceedings of the …, 2018 - National Acad Sciences
We report a strategy for generating a combinatorial library of oligonucleotide transporters
with varied lipid domains and their use in the efficient transfection of lymphocytes with …

Functional systems with orthogonal dynamic covalent bonds

A Wilson, G Gasparini, S Matile - Chemical Society Reviews, 2014 - pubs.rsc.org
This review summarizes the use of orthogonal dynamic covalent bonds to build functional
systems. Dynamic covalent bonds are unique because of their dual nature. They can be as …

New design of a disulfurating reagent: facile and straightforward pathway to unsymmetrical disulfanes by copper‐catalyzed oxidative cross‐coupling

X **ao, M Feng, X Jiang - Angewandte Chemie International …, 2016 - Wiley Online Library
A novel reagent, which introduces two sulfur atoms in one step, was designed and used for
the construction of diverse disulfanes by copper‐catalyzed oxidative cross‐coupling under …

Oligonucleotide phosphorothioates enter cells by thiol‐mediated uptake

Q Laurent, R Martinent, D Moreau… - Angewandte Chemie …, 2021 - Wiley Online Library
Oligonucleotide phosphorothioates (OPS) are DNA or RNA mimics where one phosphate
oxygen is replaced by a sulfur atom. They have been shown to enter mammalian cells much …

Structurally dynamic hydrogels derived from 1, 2-dithiolanes

GA Barcan, X Zhang, RM Waymouth - Journal of the American …, 2015 - ACS Publications
The design and generation of adaptable materials derived from structurally dynamic
polymers provides a strategy for generating smart materials that can respond to …

Cellular uptake: lessons from supramolecular organic chemistry

G Gasparini, EK Bang, J Montenegro… - Chemical …, 2015 - pubs.rsc.org
The objective of this Feature Article is to reflect on the importance of established and
emerging principles of supramolecular organic chemistry to address one of the most …