Translating therapeutic microgels into clinical applications
Y Kittel, AJC Kuehne… - Advanced Healthcare …, 2022 - Wiley Online Library
Microgels are crosslinked, water‐swollen networks with a 10 nm to 100 µm diameter and
can be modified chemically or biologically to render them biocompatible for advanced …
can be modified chemically or biologically to render them biocompatible for advanced …
Sticking together: injectable granular hydrogels with increased functionality via dynamic covalent inter‐particle crosslinking
Granular hydrogels are an exciting class of microporous and injectable biomaterials that are
being explored for many biomedical applications, including regenerative medicine, 3D …
being explored for many biomedical applications, including regenerative medicine, 3D …
[HTML][HTML] Supramolecular microgels/microgel scaffolds for tissue repair and regeneration
K Wang, Z Wang, H Hu, C Gao - Supramolecular Materials, 2022 - Elsevier
Biomedical microgels are a novel type of materials with promising perspectives for repair
and regeneration of multi-types of tissues and organs due to their highly hydrated nature …
and regeneration of multi-types of tissues and organs due to their highly hydrated nature …
Methods to characterize granular hydrogel rheological properties, porosity, and cell invasion
Granular hydrogels are formed through the packing of hydrogel microparticles and are
emerging for various biomedical applications, including as inks for 3D printing, substrates to …
emerging for various biomedical applications, including as inks for 3D printing, substrates to …
4D printing of extrudable and degradable poly (ethylene glycol) microgel scaffolds for multidimensional cell culture
Granular synthetic hydrogels are useful bioinks for their compatibility with a variety of
chemistries, affording printable, stimuli‐responsive scaffolds with programmable structure …
chemistries, affording printable, stimuli‐responsive scaffolds with programmable structure …
Exploring the role of spatial confinement in immune cell recruitment and regeneration of skin wounds
Microporous annealed particle (MAP) scaffolds are injectable granular materials comprised
of micron sized hydrogel particles (microgels). The diameter of these microgels directly …
of micron sized hydrogel particles (microgels). The diameter of these microgels directly …
Multisized photoannealable microgels regulate cell spreading, aggregation, and macrophage phenotype through microporous void space
Microgels are an emerging platform for in vitro models and guiding cell fate due to their
inherent porosity and tunability. This work describes a light‐based technique for rapidly …
inherent porosity and tunability. This work describes a light‐based technique for rapidly …
Spatial confinement modulates macrophage response in microporous annealed particle (MAP) scaffolds
Macrophages are essential in the initiation, maintenance, and transition of inflammatory
processes such as foreign body response and wound healing. Mounting evidence suggests …
processes such as foreign body response and wound healing. Mounting evidence suggests …
Macrophage‐targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis
Y Mou, GR Wu, Q Wang, T Pan, L Zhang… - Bioengineering & …, 2022 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by
the infiltration of macrophages in the fibrotic region. Currently, no therapeutic strategies …
the infiltration of macrophages in the fibrotic region. Currently, no therapeutic strategies …
Extracellular fluid viscosity regulates human mesenchymal stem cell lineage and function
Human mesenchymal stem cells (hMSCs) respond to mechanical stimuli, including stiffness
and viscoelasticity. To date, it is unknown how extracellular fluid viscosity affects hMSC …
and viscoelasticity. To date, it is unknown how extracellular fluid viscosity affects hMSC …