Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …

The brain is arguably the most complex organ. The branched and extended morphology of
nerve cells, their subcellular complexity, the multiplicity of brain cell types as well as their …

Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and …

INTRODUCTION Our textbook understanding of the nanoscale organization of the cell and
its relationship to the thousands of proteins that drive cellular metabolism comes largely from …

Fluorescence microscopy has become a ubiquitous method to observe the location of
specific molecular components within cells. However, the resolution of light microscopy is …

Axons are ultrathin membrane cables that are specialized for the conduction of action
potentials. Although their diameter is variable along their length, how their morphology is …

The nodes of Ranvier have clustered Na+ and K+ channels necessary for rapid and efficient
axonal action potential conduction. However, detailed mechanisms of channel clustering …

The hallmark of non-selective autophagy is the formation of cup-shaped phagophores that
capture bulk cytoplasm. The process is accompanied by the conjugation of LC3B to …

Proteins of the actin depolymerizing factor (ADF)/cofilin family are ubiquitous among
eukaryotes and are essential regulators of actin dynamics and function. Mammalian neurons …

Fluorescence imaging techniques play a pivotal role in our understanding of the nervous
system. The emergence of various super-resolution microscopy methods and specialized …