The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …

Nonalcoholic fatty liver disease (NAFLD) has become a serious public health issue not only
in Western countries but also in Japan. Within the wide spectrum of NAFLD, nonalcoholic …

Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

As the rates of obesity and type 2 diabetes (T2D) continue to increase globally, so does the
prevalence of metabolic dysfunction associated steatotic liver disease (MASLD). Currently …

The incidence of type 2 diabetes (T2D) has rapidly increased over recent decades, and T2D
has become a leading public health challenge in China. Compared with European …

Every year, 2 million women reach menopause in the United States, and they may spend
40% or more of their life in a postmenopausal state. In the years immediately preceding …

Hyperinsulinemia is strongly associated with type 2 diabetes. Racial and ethnic minority
populations are disproportionately affected by diabetes and obesity-related complications …

Background Metabolic syndrome over the years have structured definitions to classify an
individual with the disease. Literature review suggests insulin résistance is hallmark of these …

Background National investigations on the interaction of insulin resistance, β-cell
dysfunction, and obesity with the development of diabetes are scarce in China. We aimed to …