The gastrointestinal mucus system in health and disease

MEV Johansson, H Sjövall, GC Hansson - … reviews Gastroenterology & …, 2013 - nature.com
Mucins—large, highly glycosylated proteins—are important for the luminal protection of the
gastrointestinal tract. Enterocytes have their apical surface covered by transmembrane …

Amebiasis

R Haque, CD Huston, M Hughes… - New England journal …, 2003 - Mass Medical Soc
Infection with Entamoeba histolytica can lead to amebic colitis and to complications
including liver abscess. This review summarizes recent research on the pathogenesis and …

Role of mucus layers in gut infection and inflammation

GC Hansson - Current opinion in microbiology, 2012 - Elsevier
The intestinal mucus is an efficient system for protecting the epithelium from bacteria by
promoting their clearance and separating them from the epithelial cells, thereby inhibiting …

Microbial adhesins to gastrointestinal mucus

N Juge - Trends in microbiology, 2012 - cell.com
The gastrointestinal tract (GIT) is lined by a layer of mucus formed by mucin glycoproteins.
This layer constitutes a physical and chemical barrier between the intestinal contents and …

Role of intestinal mucins in innate host defense mechanisms against pathogens

P Dharmani, V Srivastava, V Kissoon-Singh… - Journal of innate …, 2009 - karger.com
Gastrointestinal mucins produced by goblet cells comprise the main structural components
of the mucus layer. Mucins play a critical role in the maintenance of mucosal homeostasis …

Tissue destruction and invasion by Entamoeba histolytica

KS Ralston, WA Petri - Trends in parasitology, 2011 - cell.com
Entamoeba histolytica is the causative agent of amebiasis, a disease that is a major source
of morbidity and mortality in the develo** world. The potent cytotoxic activity of the parasite …

Immunomodulatory effect of extracellular vesicles from Entamoeba histolytica trophozoites: Regulation of NETs and respiratory burst during confrontation with human …

C Díaz-Godínez, DG Ríos-Valencia… - Frontiers in Cellular …, 2022 - frontiersin.org
Parasites release extracellular vesicles (EVs) which, in some cases, modulate the host's
immune response contributing to the establishment of the infection. In this work we have …

[BOOK][B] Carbohydrate-based drug discovery, 2 volume set

CH Wong - 2003 - books.google.com
Die Suche nach Medikamenten mit neuen oder verbesserten Eigenschaften hat das
Interesse am pharmazeutischen Potenzial von Kohlenhydraten enorm verstärkt. Dies gilt …

Immune Response of Amebiasis and Immune Evasion by Entamoeba histolytica

K Nakada-Tsukui, T Nozaki - Frontiers in immunology, 2016 - frontiersin.org
Entamoeba histolytica is a protozoan parasite and the causative agent of amebiasis. It is
estimated approximately 1% of humans are infected with E. histolytica, resulting in an …

Regulation of Virulence of Entamoeba histolytica

C Marie, WA Petri Jr - Annual review of microbiology, 2014 - annualreviews.org
Entamoeba histolytica is the third-leading cause of parasitic mortality globally. E. histolytica
infection generally does not cause symptoms, but the parasite has potent pathogenic …