Targeted drug delivery—from magic bullet to nanomedicine: principles, challenges, and future perspectives

A Tewabe, A Abate, M Tamrie, A Seyfu… - Journal of …, 2021 - Taylor & Francis
Nanomedicine is an advanced version of Paul Ehrlich's “magic bullet” concept. Targeted
drug delivery is a system of specifying the drug moiety directly into its targeted body area …

Nanocarriers-mediated drug delivery systems for anticancer agents: an overview and perspectives

Z Edis, J Wang, MK Waqas, M Ijaz… - International journal of …, 2021 - Taylor & Francis
Nanotechnology has been actively integrated as drug carriers over the last few years to treat
various cancers. The main hurdle in the clinical management of cancer is the development …

The role of nanotechnology in the treatment of viral infections

L Singh, HG Kruger, GEM Maguire… - Therapeutic …, 2017 - journals.sagepub.com
Infectious diseases are the leading cause of mortality worldwide, with viruses in particular
making global impact on healthcare and socioeconomic development. In addition, the rapid …

Polymer degradation and drug delivery in PLGA‐based drug–polymer applications: A review of experiments and theories

Y Xu, CS Kim, DM Saylor, D Koo - Journal of biomedical …, 2017 - Wiley Online Library
Poly (lactic‐co‐glycolic acid)(PLGA) copolymers have been broadly used in controlled drug
release applications. Because these polymers are biodegradable, they provide an attractive …

Starch-based controlled release fertilizers: a review

BE Channab, A El Idrissi, M Zahouily… - International Journal of …, 2023 - Elsevier
Starch, as a widely available renewable resource, has the potential to be used in the
production of controlled-release fertilizers (CRFs) that support sustainable agriculture …

Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents

R Dinarvand, nima Sepehri… - International journal …, 2011 - Taylor & Francis
The effectiveness of anticancer agents may be hindered by low solubility in water, poor
permeability, and high efflux from cells. Nanomaterials have been used to enable drug …

Nanosized hydroxyapatite and other calcium phosphates: chemistry of formation and application as drug and gene delivery agents

V Uskoković, DP Uskoković - Journal of biomedical materials …, 2011 - Wiley Online Library
The first part of this review looks at the fundamental properties of hydroxyapatite (HAP), the
basic mineral constituent of mammalian hard tissues, including the physicochemical …

PLGA-based nanoparticles: A new paradigm in biomedical applications

S Sharma, A Parmar, S Kori, R Sandhir - TrAC trends in analytical chemistry, 2016 - Elsevier
Polymers were first introduced three decades ago as bioresorbable surgical devices. Since
then, polymer-based nanoparticles have been extensively studied in a variety of fields …

Electrospun nano-fibers for biomedical and tissue engineering applications: A comprehensive review

S Parham, AZ Kharazi, HR Bakhsheshi-Rad… - Materials, 2020 - mdpi.com
Pharmaceutical nano-fibers have attracted widespread attention from researchers for
reasons such as adaptability of the electro-spinning process and ease of production. As a …

Controlled release and targeted drug delivery with poly (lactic-co-glycolic acid) nanoparticles: reviewing two decades of research

A Zeb, M Gul, TTL Nguyen, HJ Maeng - Journal of Pharmaceutical …, 2022 - Springer
Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …