Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …
oxidant molecules with vastly different properties and biological functions that range from …
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Multiple roles of reactive oxygen species (ROS) and their consequences for health and
disease are emerging throughout biological sciences. This development has led …
disease are emerging throughout biological sciences. This development has led …
Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
Biomarkers of oxidative stress in metabolic syndrome and associated diseases
R Vona, L Gambardella, C Cittadini… - Oxidative medicine …, 2019 - Wiley Online Library
Metabolic syndrome (MS) represents worldwide public health issue characterized by a set of
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …
Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models
RJ Weaver, EA Blomme, AE Chadwick… - Nature Reviews Drug …, 2020 - nature.com
Drug-induced liver injury (DILI) is a patient-specific, temporal, multifactorial
pathophysiological process that cannot yet be recapitulated in a single in vitro model …
pathophysiological process that cannot yet be recapitulated in a single in vitro model …
Methods for detection of mitochondrial and cellular reactive oxygen species
Significance: Mitochondrial and cellular reactive oxygen species (ROS) play important roles
in both physiological and pathological processes. Different ROS, such as superoxide (O2•−) …
in both physiological and pathological processes. Different ROS, such as superoxide (O2•−) …
The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells
CC Winterbourn - Biochimica et Biophysica Acta (BBA)-General Subjects, 2014 - Elsevier
Background Small molecule fluorescent probes are vital tools for monitoring reactive oxygen
species in cells. Scope of review The types of probe available, the extent to which they are …
species in cells. Scope of review The types of probe available, the extent to which they are …
[HTML][HTML] Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and …
Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation,
tumor progression, and metastasis). Of the many cellular sources of ROS generation, the …
tumor progression, and metastasis). Of the many cellular sources of ROS generation, the …
Advances in measuring cancer cell metabolism with subcellular resolution
Characterizing metabolism in cancer is crucial for understanding tumor biology and for
develo** potential therapies. Although most metabolic investigations analyze averaged …
develo** potential therapies. Although most metabolic investigations analyze averaged …
A highly specific fluorescent probe for hypochlorous acid and its application in imaging microbe-induced HOCl production
Q Xu, KA Lee, S Lee, KM Lee, WJ Lee… - Journal of the American …, 2013 - ACS Publications
Oxidative stress induced by reactive oxygen species (ROS) plays crucial roles in a wide
range of physiological processes and is also implicated in various diseases, including …
range of physiological processes and is also implicated in various diseases, including …