[HTML][HTML] Understanding acquired brain injury: a review

L Goldman, EM Siddiqui, A Khan, S Jahan… - Biomedicines, 2022 - mdpi.com
Any type of brain injury that transpires post-birth is referred to as Acquired Brain Injury (ABI).
In general, ABI does not result from congenital disorders, degenerative diseases, or by brain …

MicroRNA-based therapeutics in central nervous system injuries

P Sun, DZ Liu, GC Jickling… - Journal of Cerebral …, 2018 - journals.sagepub.com
Central nervous system (CNS) injuries, such as stroke, traumatic brain injury (TBI) and
spinal cord injury (SCI), are important causes of death and long-term disability worldwide …

Immune modulation after traumatic brain injury

M Bouras, K Asehnoune, A Roquilly - Frontiers in Medicine, 2022 - frontiersin.org
Traumatic brain injury (TBI) induces instant activation of innate immunity in brain tissue,
followed by a systematization of the inflammatory response. The subsequent response …

Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions

BL Edlow, LRD Sanz, L Polizzotto, N Pouratian… - Neurocritical care, 2021 - Springer
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …

Acute traumatic coma awakening by right median nerve electrical stimulation: a randomised controlled trial

X Wu, L **e, J Lei, J Yao, J Li, L Ruan, J Hong… - Intensive Care …, 2023 - Springer
Purpose Severe traumatic brain injury (TBI) leads to acute coma and may result in
prolonged disorder of consciousness (pDOC). We aimed to determine whether right median …

[HTML][HTML] A review of the pathology and treatment of TBI and PTSD

M Monsour, D Ebedes, CV Borlongan - Experimental neurology, 2022 - Elsevier
This literature review focuses on the underlying pathophysiology of TBI and PTSD
symptoms, while also examining the plethora of stem cell treatment options to ameliorate …

Cell-based therapies for neurological disorders—the bioreactor hypothesis

SI Savitz, CS Cox Jr - Nature Reviews Neurology, 2023 - nature.com
Cell-based therapies are an emerging biopharmaceutical paradigm under investigation for
the treatment of a range of neurological disorders. Accumulating evidence is demonstrating …

Traumatic brain injury and stem cells: an overview of clinical trials, the current treatments and future therapeutic approaches

G Schepici, S Silvestro, P Bramanti, E Mazzon - Medicina, 2020 - mdpi.com
Traumatic brain injury represents physical damage to the brain tissue that induces transitory
or permanent neurological disabilities. The traumatic injury activates an important …

Cell therapy for chronic TBI: interim analysis of the randomized controlled STEMTRA trial

M Kawabori, AH Weintraub, H Imai, I Zinkevych… - Neurology, 2021 - neurology.org
Objective To determine whether chronic motor deficits secondary to traumatic brain injury
(TBI) can be improved by implantation of allogeneic modified bone marrow–derived …

Non-pharmacological interventions for traumatic brain injury

CK Davis, V Arruri, P Joshi… - Journal of Cerebral …, 2024 - journals.sagepub.com
Heterogeneity and variability of symptoms due to the type, site, age, sex, and severity of
injury make each case of traumatic brain injury (TBI) unique. Considering this, a universal …