Electrical and mechanical stimulation of cardiac cells and tissue constructs
The field of cardiac tissue engineering has made significant strides over the last few
decades, highlighted by the development of human cell derived constructs that have shown …
decades, highlighted by the development of human cell derived constructs that have shown …
[HTML][HTML] Functional acellular matrix for tissue repair
B Wang, T Qinglai, Q Yang, M Li, S Zeng, X Yang… - Materials Today Bio, 2023 - Elsevier
In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …
physicochemical properties, and functionalization potential, decellularized extracellular …
Decellularized human dermal matrix as a biological scaffold for cardiac repair and regeneration
I Belviso, V Romano, AM Sacco, G Ricci… - … in Bioengineering and …, 2020 - frontiersin.org
The complex and highly organized environment in which cells reside consists primarily of
the extracellular matrix (ECM) that delivers biological signals and physical stimuli to resident …
the extracellular matrix (ECM) that delivers biological signals and physical stimuli to resident …
Functional morphology of the cardiac jelly in the tubular heart of vertebrate embryos
J Männer, TM Yelbuz - Journal of Cardiovascular Development and …, 2019 - mdpi.com
The early embryonic heart is a multi-layered tube consisting of (1) an outer myocardial
tube;(2) an inner endocardial tube; and (3) an extracellular matrix layer interposed between …
tube;(2) an inner endocardial tube; and (3) an extracellular matrix layer interposed between …
Porous, ventricular extracellular matrix-derived foams as a platform for cardiac cell culture
To more closely mimic the native cellular microenvironment, 3D scaffolds derived from the
extracellular matrix (ECM) are being developed as alternatives to conventional 2D culture …
extracellular matrix (ECM) are being developed as alternatives to conventional 2D culture …
[HTML][HTML] The importance of matrix in cardiomyogenesis: Defined substrates for maturation and chamber specificity
Human embryonic stem cell-derived cardiomyocytes (hESC-CM) are a promising source of
cardiac cells for disease modelling and regenerative medicine. However, current protocols …
cardiac cells for disease modelling and regenerative medicine. However, current protocols …
Secretome Analysis Performed During in vitro Cardiac Differentiation: Discovering the Cardiac Microenvironment
Human pluripotent stem cells are an important tool for the study of developmental
processes, such as cardiomyogenic differentiation. Despite the advances made in this field …
processes, such as cardiomyogenic differentiation. Despite the advances made in this field …
Epicardial prestrained confinement and residual stresses: a newly observed heart ventricle confinement interface
The heart epicardial layer, with elastin as the dominant component, has not been well
investigated, specifically on how it contributes to ventricular biomechanics. In this study, we …
investigated, specifically on how it contributes to ventricular biomechanics. In this study, we …
RNA sequencing indicates age-dependent shifts in the cardiac fibroblast transcriptome between fetal, neonatal, and adult developmental ages
Cardiac fibroblasts are responsible for extracellular matrix turnover and repair in the cardiac
environment and serve to help facilitate immune responses. However, it is well established …
environment and serve to help facilitate immune responses. However, it is well established …
Heterogeneous multi-laminar tissue constructs as a platform to evaluate aortic valve matrix-dependent pathogenicity
Designing and constructing controlled in vitro cell culture platforms is imperative toward
pinpointing factors that contribute to the development of calcific aortic valve disease. A 3D …
pinpointing factors that contribute to the development of calcific aortic valve disease. A 3D …