Myopia: histology, clinical features, and potential implications for the etiology of axial elongation
Myopic axial elongation is associated with various non-pathological changes. These include
a decrease in photoreceptor cell and retinal pigment epithelium (RPE) cell density and …
a decrease in photoreceptor cell and retinal pigment epithelium (RPE) cell density and …
Scleral structure and biomechanics
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …
Scleral thickness in human eyes
S Vurgese, S Panda-Jonas, JB Jonas - PloS one, 2012 - journals.plos.org
Purpose To obtain information about scleral thickness in different ocular regions and its
associations. Methods The histomorphometric study included 238 human globes which had …
associations. Methods The histomorphometric study included 238 human globes which had …
Biomechanics of the optic nerve head
Biomechanical factors acting at the level of the lamina cribrosa (LC) are postulated to play a
role in retinal ganglion cell dysfunction and loss in glaucoma. In support of this postulate, we …
role in retinal ganglion cell dysfunction and loss in glaucoma. In support of this postulate, we …
[HTML][HTML] Biomechanical changes in the sclera of monkey eyes exposed to chronic IOP elevations
Purpose.: To characterize scleral biomechanics in both eyes of eight monkeys in which
chronic intraocular pressure (IOP) elevation was induced in one eye. Methods.: Each …
chronic intraocular pressure (IOP) elevation was induced in one eye. Methods.: Each …
[HTML][HTML] Finite element analysis predicts large optic nerve head strains during horizontal eye movements
X Wang, H Rumpel, WEH Lim… - … & visual science, 2016 - jov.arvojournals.org
Purpose: We combined finite element (FE) analysis and dynamic magnetic resonance
imaging (MRI) to estimate optic nerve head (ONH) strains during horizontal eye movements …
imaging (MRI) to estimate optic nerve head (ONH) strains during horizontal eye movements …
Finite element modeling of the human sclera: influence on optic nerve head biomechanics and connections with glaucoma
Scleral thickness, especially near the optic nerve head (ONH), is a potential factor of interest
in the development of glaucomatous optic neuropathy. Large differences in the dimensions …
in the development of glaucomatous optic neuropathy. Large differences in the dimensions …
[HTML][HTML] Scleral biomechanics in the aging monkey eye
Purpose.: To investigate the age-related differences in the inhomogeneous, anisotropic,
nonlinear biomechanical properties of posterior sclera from old (22.9±5.3 years) and young …
nonlinear biomechanical properties of posterior sclera from old (22.9±5.3 years) and young …
Age-and race-related differences in human scleral material properties
Purpose.: We tested the hypothesis that there are age-and race-related differences in
posterior scleral material properties, using eyes from human donors of European (20–90 …
posterior scleral material properties, using eyes from human donors of European (20–90 …
A review of potential novel glaucoma therapeutic options independent of intraocular pressure
Glaucoma, a progressive optic neuropathy characterized by retinal ganglion cell
degeneration and visual field loss, is the leading cause of irreversible blindness worldwide …
degeneration and visual field loss, is the leading cause of irreversible blindness worldwide …