Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Transfer function analysis of dynamic cerebral autoregulation: a white paper from the International Cerebral Autoregulation Research Network

JAHR Claassen… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral autoregulation is the intrinsic ability of the brain to maintain adequate cerebral
perfusion in the presence of blood pressure changes. A large number of methods to assess …

Translational research in traumatic brain injury

D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Continuous assessment of the cerebral vasomotor reactivity in head injury

M Czosnyka, P Smielewski, P Kirkpatrick, RJ Laing… - …, 1997 - journals.lww.com
OBJECTIVE: Cerebrovascular vasomotor reactivity reflects changes in smooth muscle tone
in the arterial wall in response to changes in transmural pressure or the concentration of …

Transcranial Doppler ultrasound: a review of the physical principles and major applications in critical care

J Naqvi, KH Yap, G Ahmad… - International journal of …, 2013 - Wiley Online Library
Transcranial Doppler (TCD) is a noninvasive ultrasound (US) study used to measure
cerebral blood flow velocity (CBF‐V) in the major intracranial arteries. It involves use of low …

Quantification of dynamic cerebral autoregulation: welcome to the jungle!

P Brassard, MA Roy, JS Burma, L Labrecque… - Clinical Autonomic …, 2023 - Springer
Purpose Patients with dysautonomia often experience symptoms such as dizziness,
syncope, blurred vision and brain fog. Dynamic cerebral autoregulation, or the ability of the …

Regulation of the cerebral circulation: bedside assessment and clinical implications

J Donnelly, KP Budohoski, P Smielewski, M Czosnyka - Critical care, 2016 - Springer
Regulation of the cerebral circulation relies on the complex interplay between
cardiovascular, respiratory, and neural physiology. In health, these physiologic systems act …

Cerebral autoregulation: an overview of current concepts and methodology with special focus on the elderly

AHEA Van Beek, JAHR Claassen… - Journal of Cerebral …, 2008 - journals.sagepub.com
Cerebral autoregulation (CA) refers to the properties of the brain vascular bed to maintain
cerebral perfusion despite changes in blood pressure (BP). Whereas classic studies have …

Neonatal cerebrovascular autoregulation

CJ Rhee, CS da Costa, T Austin, KM Brady… - Pediatric …, 2018 - nature.com
Cerebrovascular pressure autoregulation is the physiologic mechanism that holds cerebral
blood flow (CBF) relatively constant across changes in cerebral perfusion pressure (CPP) …