Optogenetics for light control of biological systems
Optogenetic techniques have been developed to allow control over the activity of selected
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
cells within a highly heterogeneous tissue, using a combination of genetic engineering and …
Advances and opportunities in the exciting world of azobenzenes
FA Jerca, VV Jerca, R Hoogenboom - Nature Reviews Chemistry, 2022 - nature.com
Azobenzenes are archetypal molecules that have a central role in fundamental and applied
research. Over the course of almost two centuries, the area of azobenzenes has witnessed …
research. Over the course of almost two centuries, the area of azobenzenes has witnessed …
Advances in the E → Z Isomerization of Alkenes Using Small Molecule Photocatalysts
Geometrical E→ Z alkene isomerization is intimately entwined in the historical fabric of
organic photochemistry and is enjoying a renaissance (Roth et al. Angew. Chem., Int. Ed …
organic photochemistry and is enjoying a renaissance (Roth et al. Angew. Chem., Int. Ed …
Molecular photoswitches in aqueous environments
Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …
precision, using light as external stimulus, and hence are ideal tools for different research …
Photocatalytic superoxide radical generator that induces pyroptosis in cancer cells
Pyroptosis, a newly characterized form of immunogenic cell death, is attracting increasing
attention as a promising approach to cancer immunotherapy. However, biocompatible …
attention as a promising approach to cancer immunotherapy. However, biocompatible …
Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Rational design in photopharmacology with molecular photoswitches
Photopharmacology is an attractive approach for achieving targeted drug action with the use
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …
Ruthenium-based photoactivated chemotherapy
S Bonnet - Journal of the American Chemical Society, 2023 - ACS Publications
Ruthenium (II) polypyridyl complexes form a vast family of molecules characterized by their
finely tuned photochemical and photophysical properties. Their ability to undergo excited …
finely tuned photochemical and photophysical properties. Their ability to undergo excited …
An overview of coumarin as a versatile and readily accessible scaffold with broad-ranging biological activities
F Annunziata, C Pinna, S Dallavalle… - International Journal of …, 2020 - mdpi.com
Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …
Mechanochemical bond scission for the activation of drugs
Pharmaceutical drug therapy is often hindered by issues caused by poor drug selectivity,
including unwanted side effects and drug resistance. Spatial and temporal control over drug …
including unwanted side effects and drug resistance. Spatial and temporal control over drug …