Free radical mechanisms in tissue injury

TF Slater - Cell function and disease, 1988 - Springer
Free radicals are molecules or molecular fragments containing a single unpaired electron. In
general, free radicals are reactive chemically, some (eg HO•) being extremely reactive …

Antioxidants/antimutagens in food

M Namiki - Critical Reviews in Food Science & Nutrition, 1990 - Taylor & Francis
Food and oxygen, the two fundamentals of human life, are in actuality involved in intricately
conflicting interactions. This review focuses on the study of these interactions. The …

Free radicals, oxidative stress, and antioxidants in human health and disease

OI Aruoma - Journal of the American oil chemists' society, 1998 - Wiley Online Library
Free radicals and other reactive oxygen species (ROS) are constantly formed in the human
body. Free‐radical mechanisms have been implicated in the pathology of several human …

[PDF][PDF] Myocardial reperfusion: a double-edged sword?

E Braunwald, RA Kloner - The Journal of clinical …, 1985 - Am Soc Clin Investig
Both the duration and severity of myocardial ischemia are important determinants ofcell
death (10); indeed, the product of the deficit of myocardial blood flow and the duration of isch …

Degeneration and regeneration of axons in the lesioned spinal cord

ME Schwab, D Bartholdi - Physiological reviews, 1996 - journals.physiology.org
For many decades, the inability of lesioned central neurons to regrow was accepted almost
as a" law of nature", and on the clinical level, spinal cord and brain lesions were seen as …

Free radicals in medicine. I. Chemical nature and biologic reactions

PA Southorn, G Powis - Mayo Clinic Proceedings, 1988 - Elsevier
Free radicals are reactive chemical species that differ from other compounds in that they
have unpaired electrons in their outer orbitals. They are capable of damaging cellular …

Mechanisms of exercise-induced muscle fibre injury

RB Armstrong, GL Warren, JA Warren - Sports medicine, 1991 - Springer
Exercise for which a skeletal muscle is not adequately conditioned results in focal sites of
injury distributed within and among the fibres. Exercise with eccentric contractions is …

Pharmacologic approach to tissue injury mediated by free radicals and other reactive oxygen metabolites

PM Reilly, HJ Schiller, GB Bulkley - The american journal of surgery, 1991 - Elsevier
Highly toxic metabolites of oxygen are generated normally by aerobic metabolism in most
cells, and this generation is often greatly increased in pathologic conditions. When this …

The influence of trehalose, taurine, cysteamine and hyaluronan on ram semen: microscopic and oxidative stress parameters after freeze–thawing process

MN Bucak, A Ateşşahin, Ö Varışlı, A Yüce, N Tekin… - Theriogenology, 2007 - Elsevier
There is a lack of information regarding lipid peroxidation and antioxidant capacity in
cryopreserved ram semen, and cryopreservation is associated with the production of …

Production of superoxide anions by a CNS macrophage, the microglia

CA Colton, DL Gilbert - FEBS letters, 1987 - Wiley Online Library
Microglia have been implicated in both physiological and pathological processes of the
brain. Their possible roles have been compared to those of macrophages and granulocytes …