The METRIC-framework for assessing data quality for trustworthy AI in medicine: a systematic review

D Schwabe, K Becker, M Seyferth, A Klaß… - NPJ Digital …, 2024 - nature.com
The adoption of machine learning (ML) and, more specifically, deep learning (DL)
applications into all major areas of our lives is underway. The development of trustworthy AI …

Stabilization challenges and aggregation in protein-based therapeutics in the pharmaceutical industry

M Rahban, F Ahmad, MA Piatyszek, T Haertlé, L Saso… - RSC …, 2023 - pubs.rsc.org
Protein-based therapeutics have revolutionized the pharmaceutical industry and become
vital components in the development of future therapeutics. They offer several advantages …

COLLAPSE: A representation learning framework for identification and characterization of protein structural sites

A Derry, RB Altman - Protein Science, 2023 - Wiley Online Library
The identification and characterization of the structural sites which contribute to protein
function are crucial for understanding biological mechanisms, evaluating disease risk, and …

Prediction of mutation-induced protein stability changes based on the geometric representations learned by a self-supervised method

SS Li, ZM Liu, J Li, YB Ma, ZY Dong, JW Hou… - BMC …, 2024 - Springer
Background Thermostability is a fundamental property of proteins to maintain their biological
functions. Predicting protein stability changes upon mutation is important for our …

[HTML][HTML] Revolutionizing Molecular Design for Innovative Therapeutic Applications through Artificial Intelligence

A Son, J Park, W Kim, Y Yoon, S Lee, Y Park, H Kim - Molecules, 2024 - mdpi.com
The field of computational protein engineering has been transformed by recent
advancements in machine learning, artificial intelligence, and molecular modeling, enabling …

Deep Learning on Local Sites for Protein Structure and Function Analysis

AWF Derry - 2024 - search.proquest.com
Understanding how the three-dimensional structure of a protein leads to its function is
important for determining disease mechanisms, develo** targeted therapeutics, and …

[CITATION][C] The METRIC-framework for assessing data quality for trustworthy AI in medicine: a systematic review

D Laurentino Schwabe - Deutsche Nationalbibliothek