The central dogma of modern biology underscores the pivotal roles proteins play in diverse
biological processes, the study of which necessitates advanced methods to produce …

Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

With the advancement of functional nanomaterials and aptamer selection technologies,
aptamer functionalized nanomaterials (AFMs) open various methods to design new sensing …

Site-specific protein modification is a widely-used biochemical tool. However, there are
many challenges associated with the development of protein modification techniques, in …

Methods for site-specific modification of proteins should be quantitative and versatile with
respect to the nature and size of the biological or chemical targets involved. They should …

One of the most effective molecular diversity techniques is phage display. This technology is
based on a direct linkage between phage phenotype and its encapsulated genotype, which …

This protocol describes the use of sortase-mediated reactions to label the N terminus of any
given protein of interest. The sortase recognition sequence, LPXTG (for Staphylococcus …

Since the development of antibody-production techniques, a number of immunoglobulins
have been developed on a large scale using conventional methods. Hybridoma technology …

M13 bacteriophage (phage) are versatile, genetically tunable nanocarriers that have been
recently adapted for use as diagnostic and therapeutic platforms. Applying p3 capsid …

Viruses are changing the biosensing and biomedicine landscape due to their multivalency,
orthogonal reactivities, and responsiveness to genetic modifications. As the most extensively …