Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …

Bovine tuberculosis is a serious infectious disease affecting a wide range of domesticated
and wild animals, representing a worldwide economic and public health burden. The …

Tumor necrosis factor (TNF) is a critical host resistance factor against tuberculosis. However,
excess TNF produces susceptibility by increasing mitochondrial reactive oxygen species …

Abattoir is the place in which the animals are slaughtered for human consumption. Abattoir
plays important role in prevention of zoonotic diseases between animals and humans like …

Despite major global efforts to eliminate tuberculosis, which is caused by Mycobacterium
tuberculosis (Mtb), this disease remains as a major plague of humanity. Several factors …

Necrosis of macrophages in the granuloma, the hallmark immunological structure of
tuberculosis, is a major pathogenic event that increases host susceptibility. Through a …

Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis (TB), is one of
the most successfully adapted human pathogens. Human-to-human transmission occurs at …

Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease,
characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in …

Mycobacterium tuberculosis (Mtb) is known to survive within macrophages by compromising
the integrity of the phagosomal compartment in which it resides. This activity primarily relies …

The elderly population is highly susceptible to develo** respiratory diseases, including
tuberculosis, a devastating disease caused by the airborne pathogen Mycobacterium …