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Personalized vaccinology: a review
At the current time, the field of vaccinology remains empirical in many respects. Vaccine
development, vaccine immunogenicity, and vaccine efficacy have, for the most part …
development, vaccine immunogenicity, and vaccine efficacy have, for the most part …
A review of HLA allele and SNP associations with highly prevalent infectious diseases in human populations
Human leucocyte antigen (HLA) alleles and single nucleotide polymorphisms (SNPs) lying
in the HLA region are known to be associated with several infectious diseases among which …
in the HLA region are known to be associated with several infectious diseases among which …
Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans
Leprosy, a chronic infectious disease caused by Mycobacterium leprae (M. leprae), was very
common in Europe till the 16th century. Here, we perform an ancient DNA study on medieval …
common in Europe till the 16th century. Here, we perform an ancient DNA study on medieval …
Human leukocyte antigen (HLA) system: genetics and association with bacterial and viral infections
The human leukocyte antigen (HLA) system is one of the most crucial host factors
influencing disease progression in bacterial and viral infections. This review provides the …
influencing disease progression in bacterial and viral infections. This review provides the …
Genetics of leprosy: today and beyond
Leprosy is a chronic infectious disease of the skin and peripheral nerves that presents a
strong link with the host genetic background. Different approaches in genetic studies have …
strong link with the host genetic background. Different approaches in genetic studies have …
Human leukocyte antigen and tumor immunotherapy
DH Liu, FF Mou, M An, P **a - … Journal of Oncology, 2023 - spandidos-publications.com
Malignant tumors seriously endanger human health and life, and restrict economic
development. Human leukocyte antigen (HLA) is the expression product of the human major …
development. Human leukocyte antigen (HLA) is the expression product of the human major …
The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions
Leprosy is a chronic disease caused by Mycobacterium leprae. Worldwide, more than
200,000 new patients are affected by leprosy annually, making it the second most common …
200,000 new patients are affected by leprosy annually, making it the second most common …
Genetic susceptibility to leprosy—from classic immune-related candidate genes to hypothesis-free, whole genome approaches
Genetics plays a crucial role in controlling susceptibility to infectious diseases by modulating
the interplay between humans and pathogens. This is particularly evident in leprosy, since …
the interplay between humans and pathogens. This is particularly evident in leprosy, since …
[HTML][HTML] CD4+ Cytotoxic T cells involved in the development of EBV-associated diseases
M Ruiz-Pablos - Pathogens, 2022 - mdpi.com
Activated cytotoxic CD4 T cells (HLA-DR+) play an important role in the control of EBV
infection, especially in cells with latency I (EBNA-1). One of the evasion mechanisms of …
infection, especially in cells with latency I (EBNA-1). One of the evasion mechanisms of …
Human genetics of mycobacterial disease
Mycobacterial diseases are caused by members of the genus Mycobacterium, acid-fast
bacteria characterized by the presence of mycolic acids within their cell walls. Claiming …
bacteria characterized by the presence of mycolic acids within their cell walls. Claiming …