Next-generation combination approaches for immune checkpoint therapy

S Goswami, KE Pauken, L Wang, P Sharma - Nature Immunology, 2024 - nature.com
Immune checkpoint therapy has revolutionized cancer treatment, leading to dramatic clinical
outcomes for a subset of patients. However, many patients do not experience durable …

Understanding glioblastoma at the single-cell level: Recent advances and future challenges

YA Yabo, DH Heiland - PLoS biology, 2024 - journals.plos.org
Glioblastoma, the most aggressive and prevalent form of primary brain tumor, is
characterized by rapid growth, diffuse infiltration, and resistance to therapies. Intrinsic …

[HTML][HTML] New-generation technologies for spatial tissue analysis, indispensable tools for deciphering intratumor heterogeneity in the development of antibody-drug …

N Radosevic-Robin, M Kossai… - Translational Breast …, 2023 - ncbi.nlm.nih.gov
Technologies allowing in situ tissue molecular analysis of the “high-plex” type (> 20
molecules per tissue section) are the 21 st century inventions that are revolutionizing our …