Advances in targeted therapy and biomarker research in thyroid cancer

M Guo, Y Sun, Y Wei, J Xu, C Zhang - Frontiers in endocrinology, 2024 - frontiersin.org
Driven by the intricacy of the illness and the need for individualized treatments, targeted
therapy and biomarker research in thyroid cancer represent an important frontier in …

Navigating the landscape of theranostics in nuclear medicine: current practice and future prospects

A Shah, A Dabhade, H Bharadia, PS Parekh… - … für Naturforschung C, 2024 - degruyter.com
Theranostics refers to the combination of diagnostic biomarkers with therapeutic agents that
share a specific target expressed by diseased cells and tissues. Nuclear medicine is an …

[HTML][HTML] An Artificial Intelligence System for Optimizing Radioactive Iodine Therapy Dosimetry

MF Georgiou, JA Nielsen, R Chiriboga… - Journal of clinical …, 2023 - mdpi.com
Thyroid cancer, specifically differentiated thyroid carcinoma (DTC), is one of the most
prevalent endocrine malignancies worldwide. Radioactive iodine therapy (RAIT) using I-131 …

Artificial Intelligence-powered automatic volume calculation in medical images–available tools, performance and challenges for nuclear medicine

T Wendler, MC Kreissl, B Schemmer… - Nuklearmedizin …, 2023 - thieme-connect.com
Volumetry is crucial in oncology and endocrinology, for diagnosis, treatment planning, and
evaluating response to therapy for several diseases. The integration of Artificial Intelligence …

An update on redifferentiation strategies for radioactive iodine-refractory differentiated thyroid carcinoma

T Pappa, L Wirth - Endocrine, 2024 - Springer
Purpose Although most patients with differentiated thyroid carcinoma (DTC) have an
excellent prognosis, a subset will experience radioactive iodine refractory (RAI-R) disease …

Limitations of the radiotheranostic concept in neuroendocrine tumors due to lineage-dependent somatostatin receptor expression on hematopoietic stem and …

N Nguyen, Y Min, J Rivière, M van der Garde, S Ghosh… - bioRxiv, 2024 - biorxiv.org
Radiopharmaceutical therapy (RPT) has become an effective treatment option for
neuroendocrine tumors (NETs) and castration-resistant prostate cancer and is in clinical …

Theranostic Surrogacy of [123I]NaI for Differentiated Thyroid Cancer Radionuclide Therapy

SB Kim, MS Lee, IH Song, HS Park… - Molecular …, 2023 - ACS Publications
Precise dosimetry has gained interest for interpreting the response assessments of novel
therapeutic radiopharmaceuticals, as well as for improving conventional radiotherapies such …

[PDF][PDF] Thyroid Cancer: Iodine-131 Intervention and Dosimetric Analysis: A Review

OS Omenka, NHA Aziz, MH Adavize, OA Olaoluwa… - Thyroid, 2024 - researchgate.net
There has been a notable global escalation in the incidence of thyroid carcinoma, with a
particularly pronounced surge of 240% in the incidence of papillary thyroid carcinoma over …

Comparison of Whole-Body Dosimetry Measurements in 131I Therapy Using Ceiling-Mounted Geiger–Müller Detectors and γ-Camera Scans: An Agreement Analysis

N Barbosa, F Niño, MT Vallejo-Ortega… - Cancer Biotherapy & …, 2023 - liebertpub.com
Background: In 131I therapies internal dosimetry is crucial for determining the mean
absorbed dose to organs at risk, particularly the bone marrow, which has a dose constraint …

The Comparison of Extreme Machine Learning and Hidden Markov Model Algorithm in Predicting The Recurrence Of Differentiated Thyroid Cancer Using SMOTE

N Aida, TH Saragih, D Kartini, RA Nugroho… - Journal of Electronics …, 2024 - jeeemi.org
Differentiated thyroid cancer is the most common type of thyroid cancer; the types in this
category are papillary, follicular, and hurthel cell carcinoma. Up to 20% of DTCs will …