The TNF family of ligands and receptors: communication modules in the immune system and beyond
The tumor necrosis factor (TNF) and TNF receptor (TNFR) superfamilies (TNFSF/TNFRSF)
include 19 ligands and 29 receptors that play important roles in the modulation of cellular …
include 19 ligands and 29 receptors that play important roles in the modulation of cellular …
The role of CD95 and CD95 ligand in cancer
Abstract CD95 (Fas/APO-1) and its ligand, CD95L, have long been viewed as a death
receptor/death ligand system that mediates apoptosis induction to maintain immune …
receptor/death ligand system that mediates apoptosis induction to maintain immune …
Life and death in peripheral T cells
PH Krammer, R Arnold, IN Lavrik - Nature Reviews Immunology, 2007 - nature.com
During the course of an immune response, antigen-reactive T cells clonally expand and then
are removed by apoptosis to maintain immune homeostasis. Life and death of T cells is …
are removed by apoptosis to maintain immune homeostasis. Life and death of T cells is …
Regulation of CD95/Fas signaling at the DISC
IN Lavrik, PH Krammer - Cell Death & Differentiation, 2012 - nature.com
Abstract CD95 (APO-1/Fas) is a member of the death receptor (DR) family. Stimulation of
CD95 leads to induction of apoptotic and non-apoptotic signaling pathways. The formation …
CD95 leads to induction of apoptotic and non-apoptotic signaling pathways. The formation …
Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translation
Recent laboratory findings suggest that it might be possible to promote cerebral plasticity
and neurological recovery after stroke by use of exogenous pharmacological or cell-based …
and neurological recovery after stroke by use of exogenous pharmacological or cell-based …
[HTML][HTML] The CD95 receptor: apoptosis revisited
The CD95 Receptor: Apoptosis Revisited: Cell Skip to Main Content Advertisement Cell This
journal offers authors two options (open access or subscription) to publish research Submit Log …
journal offers authors two options (open access or subscription) to publish research Submit Log …
Yes and PI3K bind CD95 to signal invasion of glioblastoma
Invasion of surrounding brain tissue by isolated tumor cells represents one of the main
obstacles to a curative therapy of glioblastoma multiforme. Here we unravel a mechanism …
obstacles to a curative therapy of glioblastoma multiforme. Here we unravel a mechanism …
Surviving apoptosis: life–death signaling in single cells
Tissue development and homeostasis are regulated by opposing pro-survival and pro-death
signals. An interesting feature of the Tumor Necrosis Factor (TNF) family of ligands is that …
signals. An interesting feature of the Tumor Necrosis Factor (TNF) family of ligands is that …
Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family
K Azijli, B Weyhenmeyer, GJ Peters… - Cell Death & …, 2013 - nature.com
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-based therapy is currently
evaluated in clinical studies as a tumor cell selective pro-apoptotic approach. However …
evaluated in clinical studies as a tumor cell selective pro-apoptotic approach. However …
Neuronal apoptosis in neurodegeneration
M Okouchi, O Ekshyyan, M Maracine… - Antioxidants & redox …, 2007 - liebertpub.com
Apoptosis mediates the precise and programmed natural death of neurons and is a
physiologically important process in neurogenesis during maturation of the central nervous …
physiologically important process in neurogenesis during maturation of the central nervous …