Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?
CA Akdis - Nature Reviews Immunology, 2021 - nature.com
There has been a steep increase in allergic and autoimmune diseases, reaching epidemic
proportions and now affecting more than one billion people worldwide. These diseases are …
proportions and now affecting more than one billion people worldwide. These diseases are …
Leaky gut: mechanisms, measurement and clinical implications in humans
M Camilleri - Gut, 2019 - gut.bmj.com
The objectives of this review on 'leaky gut'for clinicians are to discuss the components of the
intestinal barrier, the diverse measurements of intestinal permeability, their perturbation in …
intestinal barrier, the diverse measurements of intestinal permeability, their perturbation in …
Intestinal barrier in human health and disease
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …
protection from external factors. It consists of epithelial cells, immune cells and their …
Intestinal barrier and permeability in health, obesity and NAFLD
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …
Liver steatosis, gut-liver axis, microbiome and environmental factors. A never-ending bidirectional cross-talk
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide and
parallels comorbidities such as obesity, metabolic syndrome, dyslipidemia, and diabetes …
parallels comorbidities such as obesity, metabolic syndrome, dyslipidemia, and diabetes …
Ochratoxin A induces liver inflammation: involvement of intestinal microbiota
W Wang, S Zhai, Y **a, H Wang, D Ruan, T Zhou… - Microbiome, 2019 - Springer
Abstract Background Ochratoxin A (OTA) is a widespread mycotoxin and induces liver
inflammation to human and various species of animals. The intestinal microbiota has critical …
inflammation to human and various species of animals. The intestinal microbiota has critical …
Gut microbiota and cardiovascular disease: evidence on the metabolic and inflammatory background of a complex relationship
A Nesci, C Carnuccio, V Ruggieri… - International Journal of …, 2023 - mdpi.com
Several studies in recent years have demonstrated that gut microbiota–host interactions play
an important role in human health and disease, including inflammatory and cardiovascular …
an important role in human health and disease, including inflammatory and cardiovascular …
[HTML][HTML] Intestinal permeability in the pathogenesis of liver damage: From non-alcoholic fatty liver disease to liver transplantation
The intimate connection and the strict mutual cooperation between the gut and the liver
realizes a functional entity called gut-liver axis. The integrity of intestinal barrier is crucial for …
realizes a functional entity called gut-liver axis. The integrity of intestinal barrier is crucial for …
Gut–liver axis: how do gut bacteria influence the liver?
PC Konturek, IA Harsch, K Konturek, M Schink… - Medical …, 2018 - mdpi.com
Chronic liver diseases are a major cause of morbidity and mortality worldwide. Recently, gut
dysbiosis was identified as an important factor in the pathogenesis of liver diseases. The …
dysbiosis was identified as an important factor in the pathogenesis of liver diseases. The …
Management of hepatorenal syndrome in liver cirrhosis: a recent update
Hepatorenal syndrome (HRS) is a serious form of renal dysfunction in patients with cirrhosis
and ascites. It is an important component of the acute-on-chronic liver failure (ACLF) …
and ascites. It is an important component of the acute-on-chronic liver failure (ACLF) …