The concept of psychosis has been shaped by traditions in the concepts of mental disorders
during the last 170 years. The term “psychosis” still lacks a unified definition, but denotes a …

The question of whether there are significant changes in brain anatomy and function at
illness onset and over the early course of schizophrenia is a crucial issue with broad …

Objective: Clinical phenomenology remains the primary means for classifying psychoses
despite considerable evidence that this method incompletely captures biologically …

Objective Familial neuropsychological deficits are well established in schizophrenia but
remain less well characterized in other psychotic disorders. This study from the Bipolar …

Objective Develo** categorical diagnoses that have biological meaning within the clinical
phenotype of psychosis (schizophrenia, schizoaffective disorder, and bipolar I disorder with …

The validity of the classification of non‐affective and affective psychoses as distinct entities
has been disputed, but, despite calls for alternative approaches to defining psychosis …

Functional magnetic resonance imaging (fMRI) studies in psychiatry use various tasks to
identify case‐control differences in the patterns of task‐related brain activation. Differently …

Background Local functional connectivity (FC) indicates local or short-distance functional
interactions and may serve as a neuroimaging marker to investigate the human brain …

Cognitive impairment is an important predictor of functional outcome in patients with
schizophrenia, yet its neurobiology is still incompletely understood. Neuropathological …

Abstract Background: Schizophrenia (SZ), bipolar disorder (BD), and major depressive
disorder (MDD) are distinct diagnostic categories in current psychiatric nosology, yet there is …